66232-48-2Relevant academic research and scientific papers
Aziridination of alkenes using 2-substituted-3-acetoxyamino-quinazolin-4(3H)-ones: Changes in transition state geometry resulting from addition of trifluoroacetic acid or by an electron-withdrawing 2-substituent
Atkinson, Robert S.,Ulukanli, Sabri
, p. 771 - 776 (1999)
The effects of TFA on the competitive reactions of 3-acetoxyaminoquinazolinones 2 and 10 with methyl acrylate and with tert-butyl acrylate are interpreted as supporting a change in transition state geometry from one where (Q)C=O/ (ester)C=O overlap 7b is
CXCR3 antagonists
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, (2008/06/13)
Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.
