6625-70-3

Basic information

• Product Name: 7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one
• CAS NO: 6625-70-3
• Molecular Formula: C₅H₄N₂O₂
• Molecular Weight: 388.4126
• Mol File: 6625-70-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 579.7°C at 760 mmHg
• Flash Point: 252.9°C
• Density: 1.244g/cm³
• Vapor Pressure: 1.96E-13mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: 7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one(6625-70-3)
• EPA Substance Registry System: 7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one(6625-70-3)

Safety Data

• Hazardous Substances Data: 6625-70-3(Hazardous Substances Data)

Usage

Description

7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one, commonly known as xanthohumol, is a naturally occurring prenylated chalcone derived from the hops plant. It possesses a unique chemical structure and has been extensively studied for its potential health benefits, including anti-cancer, anti-inflammatory, and antioxidant properties. Xanthohumol's chemopreventive effects against various types of cancer, as well as its potential to prevent metabolic diseases and promote cardiovascular health, have made it a subject of interest in the field of natural product pharmacology and drug discovery.

Uses

Used in Pharmaceutical Industry:
7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one is used as a chemopreventive agent for its potential to inhibit the growth and progression of various types of cancer, including breast, prostate, and colon cancer. Its anti-cancer properties are attributed to its ability to modulate several oncological signaling pathways, exerting inhibitory effects on tumor growth and progression.
Used in Nutraceutical Industry:
7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one is used as a dietary supplement for its potential to prevent metabolic diseases and promote cardiovascular health. Its anti-inflammatory and antioxidant properties contribute to the maintenance of overall health and well-being.
Used in Drug Discovery:
7-[(4-methoxybenzyl)oxy]-4-(4-methoxyphenyl)-2H-chromen-2-one is used as a lead compound in the development of novel therapeutic agents targeting various health conditions. Its unique chemical structure and biological activities make it a promising candidate for further research and development in the field of natural product pharmacology.

Upstream product

• 108-24-7 acetic anhydride 
• 20342-65-8 2-hydroxypropanedinitrile 

Downstream Products

• 1119-49-9 N-butylacetamide 
• 1173990-32-3 2-(butylamino)-1-cyclohexyl-2-oxoethyl acetate 
• 1173990-26-5 2-amino-1-(4-methylphenyl)-2-oxoethyl acetate 
• 1173990-27-6 2-(phenylamino)-1-(4-methylphenyl)-2-oxoethyl acetate 
• 1173990-25-4 2-(butylamino)-1-(4-methylphenyl)-2-oxoethyl acetate 
• 1173990-28-7 2-(diethylamino)-1-(4-methylphenyl)-2-oxoethyl acetate 
• 1173990-30-1 1-(butylamino)-3-ethyl-1-oxopentan-2-yl acetate 
• 1173990-17-4 methyl acetoxy(4-cyanophenyl)acetate 
• 134540-60-6 methyl 2-acetoxy 3-methyl butanoate 
• 55538-79-9 methyl (+/-)-α-acetoxy-α-(4-methoxyphenyl)acetate 
• 86561-27-5 methyl O-acetylmandalate 
• 29704-42-5 4-nitromandelic acid methyl ester acetate 
• 136707-99-8 methyl (+/-)-α-acetoxy-α-(4-methylphenyl)acetate 
• 1173990-23-2 methyl 2-acetoxy-3-ethylheptanoate 

Relevant articles and documents

A three-step preparation of MAC reagents from malononitrile

An alternative method for the preparation of MAC reagents, H-C(CN)2O-R, was developed. Using the proposed method, MAC reagents with acyl moiety were synthesized from malononitrile in more than 60% overall yields in three steps.