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6625-88-3

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6625-88-3 Usage

General Description

"[3-(hydroxymethyl)phenoxy]acetic acid, also known as 3-phenoxy-1,2-propanediol, is a chemical compound with the molecular formula C8H10O4. It is a derivative of phenol and acetic acid and is often used as an intermediate in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. [3-(hydroxymethyl)phenoxy]acetic acid is synthesized through the reaction of phenol with chloroacetic acid, followed by hydrolysis. It is a white crystalline solid that is soluble in water and has a variety of applications in the chemical and pharmaceutical industries due to its ability to function as a building block in the synthesis of other organic compounds. As with any chemical, proper handling and safety precautions should be observed when working with [3-(hydroxymethyl)phenoxy]acetic acid."

Check Digit Verification of cas no

The CAS Registry Mumber 6625-88-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,2 and 5 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6625-88:
(6*6)+(5*6)+(4*2)+(3*5)+(2*8)+(1*8)=113
113 % 10 = 3
So 6625-88-3 is a valid CAS Registry Number.

6625-88-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[3-(hydroxymethyl)phenoxy]acetic acid

1.2 Other means of identification

Product number -
Other names [3-(hydroxymethyl)phenoxy]acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6625-88-3 SDS

6625-88-3Relevant articles and documents

Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin

Hidaka, Koushi,Kimura, Tooru,Ruben, Adam J.,Uemura, Tsuyoshi,Kamiya, Mami,Kiso, Aiko,Okamoto, Tetsuya,Tsuchiya, Yumi,Hayashi, Yoshio,Freire, Ernesto,Kiso, Yoshiaki

scheme or table, p. 10049 - 10060 (2009/04/07)

Plasmepsin (Plm) is a potential target for new antimalarial drugs, but most reported Plm inhibitors have relatively low antimalarial activities. We synthesized a series of dipeptide-type HIV protease inhibitors, which contain an allophenylnorstatine-dimethylthioproline scaffold to exhibit potent inhibitory activities against Plm II. Their activities against Plasmodium falciparum in the infected erythrocyte assay were largely different from those against the target enzyme. To improve the antimalarial activity of peptidomimetic Plm inhibitors, we attached substituents on a structure of the highly potent Plm inhibitor KNI-10006. Among the derivatives, we identified alkylamino compounds such as 44 (KNI-10283) and 47 (KNI-10538) with more than 15-fold enhanced antimalarial activity, to the sub-micromolar level, maintaining their potent Plm II inhibitory activity and low cytotoxicity. These results suggest that auxiliary substituents on a specific basic group contribute to deliver the inhibitors to the target Plm.

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