66269-78-1 Usage
Description
2-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine, also known as DHPD, is an organic compound with a molecular formula C10H11N. It is a pyrrole derivative with a pyridine ring, and it is commonly used as a ligand in coordination chemistry. DHPD has a unique molecular structure that gives it interesting properties, making it an important compound in various fields of research and industry.
Uses
Used in Coordination Chemistry:
2-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine is used as a ligand for the formation of coordination complexes with metal ions. Its ability to chelate metal ions allows for the development of new catalysts and functional materials.
Used in Catalysis:
2-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine is used as a catalyst or catalyst precursor in various chemical reactions. Its unique structure and properties enable it to facilitate reactions and improve their efficiency.
Used in Material Science:
2-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine is used in the development of new functional materials with specific properties. Its incorporation into materials can lead to improved performance and novel applications.
Used in Pharmaceutical and Agrochemical Synthesis:
2-(4,5-Dihydro-3H-pyrrol-2-yl)-pyridine is used as an intermediate or building block in the synthesis of pharmaceuticals and agrochemicals. Its unique structure can contribute to the development of new drugs and pesticides with enhanced efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 66269-78-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,6 and 9 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 66269-78:
(7*6)+(6*6)+(5*2)+(4*6)+(3*9)+(2*7)+(1*8)=161
161 % 10 = 1
So 66269-78-1 is a valid CAS Registry Number.
InChI:InChI=1/C17H22ClNO/c1-16(2)13-7-8-17(16,3)15(10-13)19-20-11-12-5-4-6-14(18)9-12/h4-6,9,13H,7-8,10-11H2,1-3H3/b19-15-
66269-78-1Relevant articles and documents
Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers
Lloyd, John,Finlay, Heather J.,Vacarro, Wayne,Hyunh, Tram,Kover, Alexander,Bhandaru, Rao,Yan, Lin,Atwal, Karnail,Conder, Mary Lee,Jenkins-West, Tonya,Shi, Hong,Huang, Christine,Li, Danshi,Sun, Huabin,Levesque, Paul
scheme or table, p. 1436 - 1439 (2010/07/02)
Design and synthesis of pyrazolodihydropyrimidines as KV1.5 blockers led to the discovery of 7d as a potent and selective antagonist. This compound showed atrial selective prolongation of effective refractory period in rabbits and was selected for clinical development.
Diastereoselective synthesis of cyclic 1,3-aminoalcohols bearing CF3(CCl3)-groups
Shevchenko, Nikolay E.,R?schenthaler, Gerd-Volker,Mitiaev, Alexander S.,Lork, Enno,Nenajdenko, Valentine G.
scheme or table, p. 637 - 644 (2009/04/03)
An aldol-type reaction of cyclic imines and cyclic lactims with carbonyl compounds activated by electron withdrawing trifluoromethyl or trichloromethyl groups proceeded without any catalyst under mild condition. β-Hydroxymethyl substituted cyclic imines or imidates are formed as a result of the reaction. The reduction of the prepared imines leads stereoselectively to the cyclic 1,3-aminoalcohols. Application of methyl trifluoropyruvate in this transformation opens an opportunity for the synthesis of γ-aminoacids derivatives which contain pyrrolidine moiety.
