66283-26-9 Usage
Synonyms
Lauryl lactam Other names used to refer to 1-dodecanoyl-2-pyrrolidinone.
Derivation
From lauric acid The compound is derived from lauric acid, a saturated fatty acid found in coconut oil and palm kernel oil.
Uses
Surfactant, emulsifying agent, and stabilizer Common applications of 1-dodecanoyl-2-pyrrolidinone in industrial and cosmetic products, helping to reduce surface tension, mix oil and water, and maintain product stability.
Solubility
Excellent in water The compound has a high solubility in water, which is beneficial for formulating various products.
Antimicrobial properties
Potential antimicrobial properties The compound has been found to exhibit antimicrobial activity, making it useful in personal care and pharmaceutical products for its potential to inhibit the growth of bacteria and other microorganisms.
Role
Enhancing performance and stability 1-dodecanoyl-2-pyrrolidinone plays a crucial role in improving the effectiveness and stability of various consumer and industrial products.
Check Digit Verification of cas no
The CAS Registry Mumber 66283-26-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,2,8 and 3 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 66283-26:
(7*6)+(6*6)+(5*2)+(4*8)+(3*3)+(2*2)+(1*6)=139
139 % 10 = 9
So 66283-26-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H29NO2/c1-2-3-4-5-6-7-8-9-10-12-15(18)17-14-11-13-16(17)19/h2-14H2,1H3
66283-26-9Relevant academic research and scientific papers
Sasaki,Mori,Nakamura,Shibasaki
, p. 628 - 633 (1991)
Several 1-acyl-2-pyrrolidinone derivatives were synthesized as derivatives of γ-aminobutyric acid (GABA), and their pharmacological activities and stabilities were investigated. The derivatives showed anticonvulsant effect on picrotoxin-induced seizure at a dose of 200 mg/kg. In particular, 1-decanoyl-2-pyrrolidinone (7) and 1-dodecanoyl-2-pyrrolidinone (8) had a high activity. The anticonvulsant activity showed a dose dependency. Some of 1-acyl-2-pyrrolidinone derivatives prolonged sleeping time which was induced by sodium pentobarbital and showed a recovery from disruption of the memory of passive avoidance response, which was induced by an electroconvulsive shock. As shown by the results of the stability study of 1-acetyl-2-pyrrolidinone (1), it was degraded in an acidic buffer and an alkaline buffer although 2-pyrrolidinone was stable. 1-Acyl-2-pyrrolidinone derivatives were degraded in liver and brain homogenates of mouse and rat. They showed a degradation rate in rat plasma. Conversion of 8 to GABA in mouse liver homogenate was demonstrated. These results suggested that the pharmacological activity of 1-acyl-2-pyrrolidinone is probably due to the release of GABA by hydrolysis of derivatives although further work is necessary.
