66287-29-4Relevant academic research and scientific papers
REACTIVITY OF NEW PRECURSORS OF QUINONE METHIDES
Loubinoux, Bernard,Miazimbakana, Joseph,Gerardin, Philippe
, p. 1939 - 1942 (2007/10/02)
The azidomethylene protecting group allows the synthesis of unstable phenolic compounds which are used as quinone methide precursors in the alkylations of alcohols, phenols, azide, thiophenol, amines, enols and enolates.
PROTECTION DES PHENOLS PAR LE GROUPEMENT AZIDOMETHYLENE APPLICATION A LA SYNTHESE DE PHENOLS INSTABLES
Loubinoux, Bernard,Tabbache, Samir,Gerardin, Philippe,Miazimbakana, Joseph
, p. 6055 - 6064 (2007/10/02)
Phenols are protected by the azidomethylene group in basic, nucleophilic, oxidative, weakly reductive and weakly acidic media.This group is obtained by the reaction of sodium azide with aryloxymethyl chlorides.Its utility lies in the ease with which it can be removed under very mild conditions which allows the synthesis of very unstable phenolic compounds.
