66291-33-6

Usage

InChI:InChI=1/C16H14/c1-11-7-8-14-12(2)10-13-5-3-4-6-15(13)16(14)9-11/h3-10H,1-2H3

Upstream product

• 1942-16-1 6,9-Dimethyl-1-oxo-1,2,3,4-tetrahydro-phenanthren 
• 615-42-9 1,2-Diiodobenzene 
• 595585-52-7 2-(2-isopropenyl-5-methyl-1,4-cyclohexadien-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 2315-99-3 4-(4,7-dimethyl-[1]naphthyl)-butyric acid 
• 1942-17-2 4-<4.7-Dimethyl-naphthyl-(1)>-4-oxo-buttersaeure 

Relevant academic research and scientific papers

Method for synthesizing 6-methyl phenanthridine compound

The present invention provides a method for synthesizing a 6-methyl phenanthridine compound. The method is as below: using a substituted azide terminal alkene compound represented by a formula I as astarting material, conducting a reaction in an organic solvent under the action of a copper catalyst and an oxidizing agent at 60 to 100 DEG C for 8 to 16 hours, and conducting post-treatment on the obtained reaction solution to obtain 6-methyl phenanthridine represented by a formula II and derivatives thereof, wherein the mass ratio of the substituted azide terminal alkene compound represented bythe formula I, the copper catalyst and the oxidizing agent is 1:(0.11-0.3):(1-3). The method of the present invention is safe and environmentally friendly, and does not generate waste water; the substrate has good adaptability and various substituents can be aromatized/methylated; the reaction conditions are mild, and the reaction can be carried out at a lower temperature; the raw materials do not need to be aromatized or methylated in advance; the reaction steps are simple; therefore, the method is a new route for synthesis of various 6-methyl phenanthridines containing substituents.

Dihydroaromatic boronic esters as building blocks for the synthesis of phenanthrenes and phenanthridines

Alkenyl-substituted dihydroaromatic boronic esters, generated by neutral cobalt(I)-catalysed Diels-Alder reactions, reacted under palladium catalysis conditions with diiodobenzene, bromoiodobenzene and iodoaniline derivatives for the synthesis of regioselectively substituted phenanthrene and phenanthridine derivatives. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.