663-97-8 Usage
Uses
Used in Pharmaceutical Industry:
(3beta,5alpha,17alpha)-3,14-dihydroxycard-20(22)-enolide, or digoxin, is used as a medication for the treatment of heart failure and certain types of irregular heartbeats. Its application is based on its ability to slow down the heart rate and increase the force of the heart's contractions, providing relief and improving the quality of life for patients with these conditions.
Used in Cardiology:
In the field of cardiology, digoxin is used as a therapeutic agent for managing heart failure and specific types of arrhythmias. Its use is justified by its effectiveness in regulating the heart's rhythm and improving cardiac function, which is crucial for the well-being of patients suffering from these heart conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 663-97-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,6 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 663-97:
(5*6)+(4*6)+(3*3)+(2*9)+(1*7)=88
88 % 10 = 8
So 663-97-8 is a valid CAS Registry Number.
663-97-8Relevant academic research and scientific papers
BIOTRANSFORMATION OF DIGITOXIGENIN BY GINSENG HAIRY ROOT CULTURES
Kawaguchi, Kiichiro,Hirotani, Masao,Yoshikawa, Takafumi,Furuya, Tsutomu
, p. 837 - 843 (2007/10/02)
Five new compounds (three esters and two glycosides) and seven previously reported compounds were isolated as biotransformation products of digitoxigenin by ginseng hairy root cultures.The new esters and glycosides were elucidated as digitoxigenin stearate, digitoxigenin palmitate, digitoxigenin myristate, 3-epidigitoxigenin β-D-gentiobioside and digitoxigenin β-D-sophoroside using 1H and 13C NMR and FAB mass spectral data.Biotransformations involving esterification (of stearic acid, palmitic acid, myristic acid and lauric acid) and glycosylation (of gentiobiose and sophorose) of digitoxigenin have been demonstrated for the first time in the plant cell and tissue cultures.The hairy roots showed high glycosylation ability to the digitoxigenin molecule.
