66306-10-3

Upstream product

• 609-99-4 3,5-dinitrosalicylic acid 
• 10026-13-8 phosphorus pentachloride 

Downstream Products

• 215781-76-3 C₃₂H₂₄N₄O₁₄ 
• 1415566-89-0 C₁₀H₅N₅O₈S 
• 2912-79-0 2-hydroxy-3,5-dinitrobenzamide 
• 227946-84-1 C₁₅H₁₃N₃O₆ 
• 227946-85-2 C₁₅H₂₁N₃O₆ 
• 125665-41-0 {2-Butyl-5-chloro-3-[4-(2-hydroxy-3,5-dinitro-benzoylamino)-benzyl]-3H-imidazol-4-yl}-acetic acid methyl ester 
• 22557-74-0 ethyl 3,5-dinitrosalicylate 
• 22633-33-6 methyl-3,5-dinitrosalicylate 

Relevant academic research and scientific papers

Evaluation of the anticancer properties of the predicted hBaxBH3-mimetic compound 2-hydroxy-3,5-dinitrobenzamide in a mammary carcinogenesis-induced rat model

Designing small molecular prototypes having potential to disrupt binding interfaces of pro-apoptotic-anti-apoptotic/BH3-only proteins is a promising strategy in cancer chemotherapy. Several natural and synthetic chemical compounds have been reported as in

Discovery of fluoroquinolone derivatives as potent, selective inhibitors of PI3Kγ

Phosphoinositide 3-kinase (PI3K) is an attractive target to potentially treat a range of disease states as illustrated by more than 15 inhibitors now in clinical trials. We disclose herein the discovery of a new class of fluoroquinolone derivatives having

Urea thiadiazole inhibitors of plasminogen activator inhibior-1

Methods of treating disorders associated with elevated levels of PAI-1 are disclosed comprising administering to a patient in need thereof a therapeutically effective amount of at least one compound of formula (I), or a pharmaceutically-acceptable salt, prodrug, stereoisomer or solvate thereof, wherein: A is aryl o heteroaryl, and R1-R12, are defined herein. The invention also pertains to pharmaceutical compositions and compounds within the scope of formula (I) as well as medicaments and articles of manufacture comprising compounds of formula (I).

Modulators of cysteine protease

The present invention concerns novel mediators of the activity of picornavirus 3C protease and the modulation of the activity of other similar proteins. The modulators may be used in pharmaceutical compositions either for inhibition of 3C protease (for example in viral infections) or for the enhancement of the activity of proteins similar to the 3C protease such as Apopain (for induction of apoptosis).

Synthesis and Biological Activities of 1,1′-Bis(p-substituted-benzoyloxy-substituted-phenyl)cyclohexane

1,1′-Bis(p-substituted-benzoyloxy-substituted-phenyl)cyclohexane have been synthesized. Most of the compounds exhibit promising antibacterial activity and moderate anifungal activity.