66306-10-3Relevant articles and documents
Evaluation of the anticancer properties of the predicted hBaxBH3-mimetic compound 2-hydroxy-3,5-dinitrobenzamide in a mammary carcinogenesis-induced rat model
Sivakumar, Dakshinamurthy,Surapaneni, Krishna Mohan,Prabu, Ponnachipudhur Chinnaswamy,Hari, Natarajan,Thiruvasagam, Ponnusamy,Rajasekaran, Muthu,Sivaraman, Thirunavukkarasu
, p. 2854 - 2869 (2016/01/16)
Designing small molecular prototypes having potential to disrupt binding interfaces of pro-apoptotic-anti-apoptotic/BH3-only proteins is a promising strategy in cancer chemotherapy. Several natural and synthetic chemical compounds have been reported as in
Urea thiadiazole inhibitors of plasminogen activator inhibior-1
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Page/Page column 34, (2010/02/11)
Methods of treating disorders associated with elevated levels of PAI-1 are disclosed comprising administering to a patient in need thereof a therapeutically effective amount of at least one compound of formula (I), or a pharmaceutically-acceptable salt, prodrug, stereoisomer or solvate thereof, wherein: A is aryl o heteroaryl, and R1-R12, are defined herein. The invention also pertains to pharmaceutical compositions and compounds within the scope of formula (I) as well as medicaments and articles of manufacture comprising compounds of formula (I).
Synthesis and Biological Activities of 1,1′-Bis(p-substituted-benzoyloxy-substituted-phenyl)cyclohexane
Rajkotia,Parsania
, p. 524 - 525 (2007/10/03)
1,1′-Bis(p-substituted-benzoyloxy-substituted-phenyl)cyclohexane have been synthesized. Most of the compounds exhibit promising antibacterial activity and moderate anifungal activity.