6631-61-4

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-phenylhydrazinyl)heptose is used as a building block for the synthesis of new drugs and biologically active molecules due to its enhanced reactivity and potential biological activity.
Used in Antimicrobial Applications:
1-(2-phenylhydrazinyl)heptose is used as an antimicrobial agent for the development of new antimicrobial agents, as studies have shown that it possesses antimicrobial properties.

Upstream product

• 6027-89-0 L-gulose 
• 100-63-0 phenylhydrazine 
• 221129-02-8 (4S,5R)-3,4-Dihydroxy-5-((1S,2R)-1,2,3-trihydroxy-propyl)-dihydro-furan-2-one 
• 882983-01-9 D-glycero-L-talo-heptonic acid 

Downstream Products

• 3960-52-9 D-glycero-L-gluco-Heptose-dibenzyldithioacetal 

Relevant academic research and scientific papers

Highly functionalised cyclopentanes by radical cyclisation of unsaturated bromolactones III. Preparation of carbaaldohexofuranoses. Determination of the relative configuration at C-4/C-5 of 2,3-unsaturated heptono-1,4-lactones by means of 1H NMR spectroscopy

Two new carbaaldohexofuranoses, carba-β-D-glucofuranose and carba-α- L-mannofuranose, have been prepared using 5,6-O-isopropylidene-D-glycero-L- galacto-heptono-1,4-lactone (6) as the starting material. The key step was a highly stereoselective intramolecular 5-exo-trig radical cyclisation of C-2 substituted 2,3-unsaturated 7-bromo-7-deoxyheptono-1,4-lactones promoted by tributyltin hydride. Assignment of the configuration of the unsaturated lactones was based upon NMR data of related compounds. The starting material, compound 6, was obtained by chain elongation of D-gulose, and a facile method for separation of the epimers from the chain elongation has been developed. Thus 5,6-O-isopropylidene-D-glycero-L-galacto-heptono-1,4-lactone (6) and D- glycero-L-taloheptono-1,4-lactone (5) were isolated crystalline in ca. 30% and 10% yield, respectively.