66312-71-8

Upstream product

• 102-96-5 (2-nitroethenyl)benzene 
• 66312-68-3 4-(1-cyclohex-1-enyl-vinyl)-morpholine 
• 932-66-1 1-cyclohexenyl methyl ketone 
• 5153-67-3 nitrostyrene 

Downstream Products

• 66312-72-9 (3S,4R,4aR,8aS)-4-Nitro-3-phenyl-octahydro-naphthalen-1-one 
• 66312-72-9 (3S,4R,4aS,8aS)-4-Nitro-3-phenyl-octahydro-naphthalen-1-one 
• 66312-72-9 (3R,4R,4aR,8aR)-4-Nitro-3-phenyl-octahydro-naphthalen-1-one 

Relevant academic research and scientific papers

Organocatalytic asymmetric Michael addition of 1-acetylcyclohexene and 1-acetylcyclopentene to nitroolefins

Enantioselective organocatalytic Michael addition reactions of 1-acetylcyclohexene, 1-acetylcyclopentene and 1-acetylcyclobutene to nitroolefins have been developed. This is the first report where an α-branched enone has been activated by an amine catalyst for the asymmetric Michael addition reaction to an electrophile. The Michael products have also been cyclized to bicyclic compounds.

SYNTHESIS OF NITRO-SUBSTITUTED DECALONES BY DOUBLE MICHAEL REACTION, SEQUENTIAL MICHAEL REACTION, AND BY DIELS ALDER REACTION

4-Nitro-3-phenyl-decalones are obtained from 1-acetylcyclohexene by three different ways.Stereochemistry and reaction pathways are discussed, and, for the first time, an intermediate of a sequential Michael reaction is isolated.