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4,4,4-Trifluoro-3-oxo-N-M-tolyl-butyraMide, also known as trifluridine, is a synthetic nucleoside analog that exhibits antiviral and anticancer properties. It functions by inhibiting DNA synthesis, thereby preventing the replication of viruses and cancer cells. Trifluridine is particularly effective against herpes viruses such as herpes simplex virus (HSV) and varicella-zoster virus (VZV), as well as certain types of cancer, including colorectal cancer and eye tumors.

663191-97-7

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663191-97-7 Usage

Uses

Used in Antiviral Applications:
4,4,4-Trifluoro-3-oxo-N-M-tolyl-butyraMide is used as an antiviral agent for inhibiting the replication of herpes viruses, specifically herpes simplex virus (HSV) and varicella-zoster virus (VZV). Its mechanism of action involves the interference with DNA synthesis, leading to the suppression of viral replication and reducing the severity of viral infections.
Used in Anticancer Applications:
In the field of oncology, 4,4,4-Trifluoro-3-oxo-N-M-tolyl-butyraMide is used as an anticancer medication, particularly effective against colorectal cancer and eye tumors. It targets the DNA synthesis process in cancer cells, thereby inhibiting their growth and proliferation.
Used in Pharmaceutical Industry:
4,4,4-Trifluoro-3-oxo-N-M-tolyl-butyraMide is used as a pharmaceutical agent for the development of antiviral and anticancer medications. Its unique ability to target DNA synthesis in both viruses and cancer cells makes it a valuable compound in the creation of therapeutic treatments for these conditions.
Used in Ophthalmology:
In ophthalmology, 4,4,4-Trifluoro-3-oxo-N-M-tolyl-butyraMide is used as a treatment for eye tumors and viral infections affecting the eye. It is typically administered as eye drops, providing a targeted approach to treating ocular conditions while minimizing systemic side effects.
Side effects of trifluridine may include irritation at the application site, blurred vision, and eye discomfort. It is crucial to use this medication only as directed by a healthcare professional to ensure its safety and effectiveness.

Check Digit Verification of cas no

The CAS Registry Mumber 663191-97-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,3,1,9 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 663191-97:
(8*6)+(7*6)+(6*3)+(5*1)+(4*9)+(3*1)+(2*9)+(1*7)=177
177 % 10 = 7
So 663191-97-7 is a valid CAS Registry Number.

663191-97-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,4,4-trifluoro-N-(3-methylphenyl)-3-oxobutanamide

1.2 Other means of identification

Product number -
Other names 4,4,4-Trifluoro-3-oxo-N-m-tolyl-butyramide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:663191-97-7 SDS

663191-97-7Relevant academic research and scientific papers

An Improved Access to 4-Trifluoromethyl-2(1H)-quinolinones: The "Watering Protocol"

Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred

, p. 54 - 63 (2007/10/03)

Condensation of anilines with ethyl 4,4,4-trifluoroacetoacetate (7) to afford the corresponding 4,4,4-trifluoro-3-oxobutaneanilides (10), precursors to 4-(trifluoromethyl)-2-quinolinones (11), can be favored and the competing condensation to produce the e

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