66340-33-8

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Basic information

Product Name: 3-Desacetyl CefotaxiMe Lactone
Synonyms: 3-Desacetyl CefotaxiMe Lactone;[5aR-[5aα,6β(Z)]]-2-AMino-α-(MethoxyiMino)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-4-thiazoleacetaMide;3-Desacetyl CefotaxiMe Lactone (IMpurity E);Ceftriaxone IMpurity B;CefotaxiMe Related CoMpound E;Cefotaxime EP Impurity B;Ceftriaxone Sodium EP Impurity B(Cefotaxime EP Impurity E);Deacetylcefotaxime lactone ,Cefotaxime Impurity E (EP)
CAS NO:66340-33-8
Molecular Formula: C₁₄H₁₃N₅O₅S₂
Molecular Weight: 395.41352
EINECS: N/A
Product Categories: Impurity;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File: 66340-33-8.mol
Article Data: 2

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: 1.99±0.1 g/cm3(Predicted)
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
PKA: 8.25±0.20(Predicted)
CAS DataBase Reference: 3-Desacetyl CefotaxiMe Lactone(CAS DataBase Reference)
NIST Chemistry Reference: 3-Desacetyl CefotaxiMe Lactone(66340-33-8)
EPA Substance Registry System: 3-Desacetyl CefotaxiMe Lactone(66340-33-8)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 66340-33-8(Hazardous Substances Data)

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66340-33-8 Usage

Uses

3-Desacetyl Cefotaxime Lactone is an impurity of Cefotaxime sodium (C242950). 3-Desacetyl Cefotaxime Lactone is also a degradation product for other cephalosporin antibiotics such as: Ceftriaxone (C245000), Cefodizime and Ceftiofur (C244700).

Check Digit Verification of cas no

The CAS Registry Mumber 66340-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,3,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 66340-33:
(7*6)+(6*6)+(5*3)+(4*4)+(3*0)+(2*3)+(1*3)=118
118 % 10 = 8
So 66340-33-8 is a valid CAS Registry Number.

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USP
(1097953) Cefotaxime Related Compound E United States Pharmacopeia (USP) Reference Standard
66340-33-8
1097953-15MG
14,500.98CNY
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66340-33-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name	3-Desacetyl Cefotaxime Lactone

1.2 Other means of identification

Product number	-
Other names	[5aR-[5a\|A,6\|A(Z)]]-2-Amino-\|A-(methoxyimino)-N-(1,4,5a,6-tetrahydro-1,7-dioxo-3H,7H-azeto[2,1-b]furo[3,4-d][1,3]thiazin-6-yl)-4-thiazoleacetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:66340-33-8 SDS

66340-33-8Upstream product

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66340-33-8Relevant articles and documents

Acidic degradation of cefodizime (THR-221) and structural elucidation of the products. I

Marunaka,Matsushima,Minami,Azuma,Yoshida,Umeno

, p. 367 - 372 (2007/10/02)

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