66340-33-8 Usage
Uses
Used in Pharmaceutical Industry:
3-Desacetyl CefotaxiMe Lactone is used as an impurity marker for [application reason] ensuring the quality and purity of Cefotaxime sodium and related cephalosporin antibiotics. Its identification and control are crucial in maintaining the safety and efficacy of these life-saving drugs.
Additionally, as a degradation product, 3-Desacetyl CefotaxiMe Lactone is used in the study of the stability and shelf life of cephalosporin antibiotics such as Ceftriaxone, Cefodizime, and Ceftiofur. Understanding the degradation pathways and the formation of 3-Desacetyl CefotaxiMe Lactone can help in the development of more stable and effective antibiotic formulations.
In Quality Control:
3-Desacetyl CefotaxiMe Lactone is used as a reference compound for [application reason] quality control testing in the manufacturing process of cephalosporin antibiotics. Its presence is monitored to ensure that the production process meets the required standards and that the final product is free from harmful impurities.
In Research and Development:
3-Desacetyl CefotaxiMe Lactone is utilized as a research compound for [application reason] investigating the mechanisms of antibiotic degradation and the factors that influence the stability of cephalosporin antibiotics. This knowledge can contribute to the improvement of drug formulations and the development of new, more stable antibiotics to combat bacterial resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 66340-33-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,3,4 and 0 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 66340-33:
(7*6)+(6*6)+(5*3)+(4*4)+(3*0)+(2*3)+(1*3)=118
118 % 10 = 8
So 66340-33-8 is a valid CAS Registry Number.
66340-33-8Relevant academic research and scientific papers
Determination of cephalosporins and decomposition products by liquid chromatography with indirect electrochemical detection
Fabre,Kok
, p. 136 - 141 (2007/10/02)
Indirect electrochemical detection, using in-line electrochemically generated bromine as oxidizing agent, has been used for the determination of cephalosporins with liquid chromatography. The method presents a general detection principle for cephalosporins since it is related to their basic structure. The detection limits obtained, which were between 0. 4 and 3 ng, and the repeatability with a relative standard deviation below 1. 5% comply with the requirements for drug stability studies in vitro.
