66346-59-6

Basic information

• Product Name: 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98
• Synonyms: 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98;5,7-DIHYDROXY-4-PROPYL-CHROMEN-2-ONE;5,7-DIHYDROXY-4-PROPYLCOUMARIN AKYL (OR ARYL) COUMARINS;5,7-Dihydroxy-4-propylcoumarin 98%;5,7-dihydroxy-4-propyl-2-chromenone
• CAS NO: 66346-59-6
• Molecular Formula: C₁₂H₁₂O₄
• Molecular Weight: 220.22128
• Product Categories: Building Blocks;Chemical Synthesis;Coumarins;Heterocyclic Building Blocks
• Mol File: 66346-59-6.mol
• Article Data: 20

Chemical Properties

• Melting Point: 239 °C (dec.)(lit.)
• Boiling Point: 470.1°C at 760 mmHg
• Flash Point: 188.5°C
• Appearance: /
• Density: 1.326g/cm³
• Vapor Pressure: 1.84E-09mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98(CAS DataBase Reference)
• NIST Chemistry Reference: 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98(66346-59-6)
• EPA Substance Registry System: 5 7-DIHYDROXY-4-PROPYLCOUMARIN 98(66346-59-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 66346-59-6(Hazardous Substances Data)

Usage

General Description

5,7-Dihydroxy-4-propylcoumarin 98 is a chemical compound that is used in various pharmaceutical and research applications. It is a derivative of coumarin, which is known for its anticoagulant and anti-inflammatory properties. This specific compound, with a purity of 98%, has a molecular formula of C11H12O4 and a molecular weight of 208.21 g/mol. It is primarily utilized as a precursor in the synthesis of new pharmaceutical compounds and in the development of anticoagulant medications. Additionally, it is also used in research studies to investigate its potential therapeutic applications and biological effects.

InChI:InChI=1/C12H12O4/c1-2-3-7-4-11(15)16-10-6-8(13)5-9(14)12(7)10/h4-6,13-14H,2-3H2,1H3

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 3249-68-1 ethyl butyroyl acetate 
• 30414-54-1 methyl 3-oxohexanoate 
• 6099-90-7 1,3,5-Trihydroxybenzene dihydrate 
• 101169-75-9 diacetoxy-5,7 propyl-4 coumarine 

Downstream Products

• 166983-58-0 5,7-Dihydroxy-8-propanoyl-4-propyl-2H-1-benzopyran-2-one 
• 1604838-59-6 C₂₃H₁₇NO₆ 
• 1604838-58-5 5-hydroxy-2-phenyl-10-propyl-8-oxo-2H,8H-pyrano[2,3-f]chromen-6-carbaldehyde 
• 1604838-91-6 5-(4-fluorobenzyloxy)-8-nitro-4-propyl-2H-furo[2,3-h]chromen-2-one 
• 1604838-93-8 5-(4-fluorophenyl)-8-nitro-4-propyl-2H-furo[2,3-h]chromen-2-one 
• 1005322-86-0 5-hydroxy-8-(4-methylphenyl)-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione 
• 1005322-84-8 5-hydroxy-8-phenyl-4-propyl-8,9-dihydro-2H,10H-pyrano[2,3-f]chromene-2,10-dione 
• 1005322-85-9 5-hydroxy-8-phenyl-4-propyl-7,8-dihydro-2H,6H-pyrano[3,2-g]chromene-2,6-dione 
• 303007-20-7 2-oxo-4-propyl-2H-chromene-5,7-diyl bis(4-methylbenzenesulfonate) 
• 5022-20-8 mammea B/BB 
• 142632-32-4 (+)-calanolide A 
• 161753-49-7 (+/-)-Calanolide D 
• 161753-49-7 (+/-)-12-oxocalanolide A 
• 303007-22-9 2,2-dimethyl-8-oxo-10-propyl-2H,8H-pyrano[2,3-f]chromen-5-yl 4-methylbenzenesulfonate 

Relevant articles and documents

N-Oxide heterocycles and imidazoles replacing ring D of calanolides against Mycobacterium tuberculosis

We have explored the chemistry of N-oxide heterocycles and imidazoles replacing ring D of the natural product (+)-calanolide A, and have synthesized 12 new analogues, two of which were active against both R Mtb and NR Mtb with MIC values of 12.5 μg/mL, which would lead to further optimization for more potent anti-TB candidates.

1-Nicotinoylbenzotriazole: A Convenient Tool for Site-Selective Protection of 5,7-Dihydroxycoumarins

1-Nicotinoylbenzotriazole (NicBt) was uncovered as an efficient protecting agent for the site-selective acylation of resorcinol-type phenolic groups with almost equal reactivity. The use of NicBt allows selective protection of the 7-OH group in 5,7-dihydr

TETRIACYCLODIPYRANYL COUMARINS AND THE ANTI-HIV AND ANTI-TUBERCULOSIS USES THEREOF

The present invention relates to tctracyclodipyrano-coumarin compounds of general formula (I), wherein the substituents are defined herein. These compounds exihibit dual biological activities of anti human immunodeficiency virus type 1 (HIV-1) infection a