66357-41-3

Usage

Uses

Used in Pharmaceutical Industry:
2-[[1-(METHYLAMINO)-2-NITROETHENYL]AMINO]-ETHANETHIOL is used as a building block for the synthesis of pharmaceuticals with anti-tumor and anti-inflammatory properties. Its ability to inhibit the growth of cancer cells makes it a promising candidate for anti-cancer therapies.
Used in Drug Synthesis:
2-[[1-(METHYLAMINO)-2-NITROETHENYL]AMINO]-ETHANETHIOL is used as a key intermediate in the synthesis of various drugs, including those with potential applications in treating bacterial infections.
Used in Dye Industry:
2-[[1-(METHYLAMINO)-2-NITROETHENYL]AMINO]-ETHANETHIOL is used in the synthesis of dyes, contributing to the development of new colorants for various applications.

InChI:InChI=1/C5H11N3O2S/c1-6-5(4-8(9)10)7-2-3-11/h4,6-7,11H,2-3H2,1H3/b5-4+

Upstream product

• 66357-40-2 2-(nitromethylene)thiazolidine 
• 74-89-5 methylamine 

Relevant academic research and scientific papers

Method for synthesizing ranitidine

A method for synthesizing ranitidine includes following steps: 1), dropwise adding sodium hydroxide water solution into 1, 1, 2-trichloroethane at 30-35 DEG C for reaction to obtain vinylidene chloride, wherein a mass ratio of 1, 1, 2-trichloroethan to sodium hydroxide is 1:0.3-0.33; 2), dropwise adding vinylidene chloride into mixed acid of concentrated hydrochloric acid and concentrated nitric acid at 20-25 DEG C for reaction for 2-4h, wherein a consumption ratio of vinylidene chloride to the mixed acid is 1:2-3; 3), adding cysteamine hydrochloride into sodium hydroxide and potassium hydroxide solution, and dropwise adding a product of the step 2) at 50-55 DEG C to obtain a closed-loop product; 4), enabling the closed-loop product to react with alcohol or methanol solution at room temperature for 14-18h to obtain an open-loop product; 5), adding the open-loop product and 2-[(dimethylamino)methyl]-5 chloromethyl-furan into potassium hydroxide or sodium hydroxide water solution for reaction at 40-50 DEG C for 2-4h to obtain ranitidine. The method lowers potential safety hazards and is simple and easy for industrial production.