6636-71-1

Basic information

• Product Name: 2-[(Pyridin-2-ylmethyl)amino]ethanol
• Synonyms: (2-hydroxyethyl)(2-pyridylmethyl)amine;2-[(PYRIDIN-2-YLMETHYL)-AMINO]-ETHANOL;N-(2-Hydroxyethyl)-2-picolylamine;Ethanol, 2-[ (2-pyridinylmethyl)amino]-;2-[(2-PYRIDINYLMETHYL)AMINO]-ETHANO;2-(2-Pyridylmethylamino)ethanol;2-[(2-Pyridinylmethyl)amino]ethanol
• CAS NO: 6636-71-1
• Molecular Formula: C₈H₁₂N₂O
• Molecular Weight: 152.19
• Product Categories: Alkohols
• Mol File: 6636-71-1.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 299°C
• Flash Point: 135°C
• Appearance: /
• Density: 1.100
• Vapor Pressure: 0.000558mmHg at 25°C
• Refractive Index: 1.543
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-[(Pyridin-2-ylmethyl)amino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(Pyridin-2-ylmethyl)amino]ethanol(6636-71-1)
• EPA Substance Registry System: 2-[(Pyridin-2-ylmethyl)amino]ethanol(6636-71-1)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 6636-71-1(Hazardous Substances Data)

Usage

Uses

2-[(Pyridin-2-ylmethyl)-amino]-ethanol can be used for synthesis, characterization, anti-bacterial and anti-tumoral activities.

InChI:InChI=1/C8H12N2O/c11-6-5-9-7-8-3-1-2-4-10-8/h1-4,9,11H,5-7H2

Upstream product

• 105516-38-9 2-[2]pyridylmethylenamino-ethanol 
• 1121-60-4 pyridine-2-carbaldehyde 
• 141-43-5 ethanolamine 
• 105516-38-9 N-(2-hydroxyethyl)-2-pyridinecarboxaldimine 

Downstream Products

• 852634-51-6 2,2-(2-hydroxy-5-methyl-1,3-phenylene)bis(methylene)bis ((pyridin-2-ylmethyl)azanediyl)diethanol 
• 1391424-41-1 ethyl 4-hydroxy-3,5-bis(((2-hydroxyethyl)(pyridin-2-ylmethyl)amino)methyl)benzoate 
• 948588-44-1 C₂₅H₂₅N₃O₃S 

Relevant articles and documents

Probing the effect of arm length and inter- and intramolecular interactions in the formation of Cu(II) complexes of Schiff base ligands derived from some unsymmetrical tripodal amines

The syntheses of two previously known, 2-((2-aminoethyl)(pyridin-2-ylmethyl)amino)ethanol (1) and 2-((3-aminopropyl)(pyridin-2-ylmethyl)amino)ethanol (2), and four new unsymmetrical N-capped tripodal amines, 2-((4-aminobutyl)(pyridin-2-ylmethyl)amino)ethanol (3), 3-((2-aminoethyl)(pyridin-2-ylmethyl)amino)propan-1-ol (4), 3-((3-aminopropyl)(pyridin-2-ylmethyl)amino)propan-1-ol (5) and 3-((4-aminobutyl)(pyridin-2-ylmethyl)amino)propan-1-ol (6), are reported. The ligands (3-4) feature a longer arm, 3-hydroxypropyl or butylamino, than in the analogues previously employed (2-hydroxyethyl arm, ethylamino-arm or propylamino-arm in 1 and 2). All six tripodal amines, 1-6, are equipped with a 2-methylpyridyl-arm and either an ethylamino-arm (1 and 4), propylamino-arm (2 and 5) or butylamino-arm (3 and 6). The new amines, 3-6, have been employed in one pot condensation reactions with 2-hydroxy-1-naphthaldehyde and salicylaldehyde (and its derivatives) in the presence of Cu(II) metal ions to generate a series of new mononuclear complexes, [MIILaldi](ClO4) as well as new dinuclear complexes [CuIILaldi]2(ClO4)2 of new ligands Laldi. Four monomeric complexes and one dimeric complex have been characterised by single crystal X-ray diffraction, revealing a distorted square-pyramidal copper(II) ion. A general comparison between these structures shows that the number and types of chelate ring sequences around the metal ions are important in the formation of structures. Theoretical studies show that the 3-hydroxypropyl arm in these complexes is a weak coordinating group and it can readily be removed from the coordination sphere of metal ions, resulting in a dimerised four coordinate complex. Calculations show that the interaction between the two monomeric fragments is very weak.

Compound for detecting brassicaceous vegetable sclerotinia sclerotiorum and application thereof

The invention discloses a compound for detecting brassicaceous vegetable sclerotinia sclerotiorum, wherein the structure of the compound is shown in the specification, wherein in the formula, R1 is selected from hydrogen and halogen; R2 is selected from hydrogen and halogen; R3 is selected from hydrogen and halogen; R4 is selected from hydrogen and halogen; and R5 is selected from hydrogen and halogen. The compound provided by the invention can realize rapid detection of brassicaceous vegetable sclerotinia sclerotiorum, has the characteristics of high accuracy, low operation difficulty, short time consumption and the like, and is worthy of popularization and application.

A selective and sensitive near-infrared fluorescent probe for real-time detection of Cu(i)

The disruption of copper homeostasis (Cu+/Cu2+) may cause neurodegenerative disorders. Thus, the need for understanding the role of Cu+ in physiological and pathological processes prompted the development of improved methods of Cu+ analysis. Herein, a new near-infrared (NIR) fluorescent turn-on probe (NPCu) for the detection of Cu+ was developed based on a Cu+-mediated benzylic ether bond cleavage mechanism. The probe showed high selectivity and sensitivity toward Cu+, and was successfully applied for bioimaging of Cu+ in living cells. This journal is

Zinc-Catalyzed Esterification of N-β-Hydroxyethylamides: Removal of Directing Groups under Mild Conditions

Amide transformations involving C–N bond cleavage are recognized as difficult reactions owing to the inert nature of amides resulting from resonance. Accordingly, a strong inductive effect and geometrical distortion reasonably decrease the resonance stabilization to attenuate the C–N linkage. Although the conversion of such activated amides has been studied intensively, reaction systems for “unactivated” amides are underdeveloped. We herein report that a zinc(II) trifluoromethanesulfonate [Zn(OTf)2] catalyst achieves the esterification of a wide range of unactivated tertiary amides with the assistance of intramolecular acyl rearrangement. The reaction was applied to the one-pot removal of various amide-based directing groups under mild reaction conditions to afford the corresponding esters in high yields.