6638-49-9Relevant articles and documents
Multiple solid forms of 1,5-Bis(salicylidene)carbohydrazide: Polymorph-modulated thermal reactivity
Rubcic, Mirta,Galic, Nives,Halasz, Ivan,Jednacak, Tomislav,Judas, Nenad,Plavec, Janez,Sket, Primoz,Novak, Predrag
, p. 2900 - 2912 (2014)
1,5-Bis(salicylidene)carbohydrazide, prepared by a condensation reaction of salicylaldehyde and carbohydrazide, afforded a diversity of crystalline forms depending on crystallization conditions: three polymorphs (I, II, and III) and two solvates (IV and V
Development of hydrazide based fluorescence probe for detection of Al3+ ions and application in live cell image
D., Anu,M., V. Kaveri,P., Naveen,R., Rajamanikandan
, (2021)
Development of highly specific and susceptible sensors for aluminium (Al3+ ions) determination in water medium is still a remarkable task. Herein, a fluorescence probe (SCH) is derived from the condensation of salicyaldehyde and carbohydrazide
Copper(II) complexes with 1,5-bis(2-hydroxybenzaldehyde)carbohydrazone
Dragancea, Diana,Shova, Sergiu,Enyedy, éva A.,Breza, Martin,Rapta, Peter,Carrella, Luca M.,Rentschler, Eva,Dobrov, Anatolie,Arion, Vladimir B.
, p. 180 - 192 (2014)
The acid-base properties of 1,5-bis(2-hydroxybenzaldehyde)carbohydrazone (H4L) and its thioanalogue 1,5-bis(2-hydroxybenzaldehyde) thiocarbohydrazone (H4LS) have been studied experimentally by pH-potentiometry and UV-Vis s
DNA binding and cytotoxicity of some Cu(II)/Zn(II) complexes containing a carbohydrazone Schiff base ligand along with 1,10-phenanthroline as a coligand
Koley, Manjuri K.,Duraipandy, Natarajan,Kiran, Manikantan Syamala,Varghese, Babu,Manoharan, Periakaruppan T.,Koley, Aditya P.
, p. 538 - 550 (2017)
We report the synthesis, characterization and biological activities of the complexes [Cu(o-phen)HL] (1), [Cu(o-phen)LCu(OAc)] (2), and [Zn(o-phen)LCu(OAc)] (3), where, H3L?=?o-HOC6H4C(H)[dbnd]N–NH–C(OH)[dbnd]N–N[dbnd]C(H)–C6H4OH-o, o-phen?=?1,10-phenanthroline, and OAc?=?CH3COO?. The free ligand and compound 3 have been characterized by X-ray crystallography. A four-line EPR pattern originating from the interaction of the unpaired electron with the central 63/65Cu nucleus (I?=?3/2) with the isotropic coupling constant (Aiso) value of 80?±?1.5?G at RT for compound 1 in DMF suggests its monomeric nature in solution. These compounds undergo irreversible oxidation-reduction. Biological studies show intercalative DNA binding and remarkable cell cytotoxicity as well as anticancer activity. The IC50 values of 1, 2 and 3 for the human lung cancer A549 cell line (0.44, 0.22, and 4.80?μM, respectively) and for the breast cancer MCF7 cell line (2.7, 4.1, and 3.6?μM, respectively) are found to be very promising and appear to be more potent than some anticancer drugs tested for these cell lines. Most importantly, 3 is found to be remarkably less toxic for HaCaT and L132 normal cell lines as evident from the cell viabilities of these two cell lines in presence of this compound.
Liquid-phase oxidation of olefins with rare hydronium ion salt of dinuclear dioxido-vanadium(V) complexes and comparative catalytic studies with analogous copper complexes
Maurya, Abhishek,Haldar, Chanchal
, (2021/02/26)
Homogeneous liquid-phase oxidation of a number of aromatic and aliphatic olefins was examined using dinuclear anionic vanadium dioxido complexes [(VO2)2(salLH)]? (1) and [(VO2)2(NsalLH)]? (2) and dinuclear copper complexes [(CuCl)2(salLH)]? (3) and [(CuCl)2(NsalLH)]? (4) (reaction of carbohydrazide with salicylaldehyde and 4-diethylamino salicylaldehyde afforded Schiff-base ligands [salLH4] and [NsalLH4], respectively). Anionic vanadium and copper complexes 1, 2, 3, and 4 were isolated in the form of their hydronium ion salt, which is rare. The molecular structure of the hydronium ion salt of anionic dinuclear vanadium dioxido complex [(VO2)2(salLH)]? (1) was established through single-crystal X-ray analysis. The chemical and structural properties were studied using Fourier transform infrared (FT-IR), ultraviolet–visible (UV–Vis), 1H and 13C nuclear magnetic resonance (NMR), electrospray ionization mass spectrometry (ESI-MS), electron paramagnetic resonance (EPR) spectroscopy, and thermogravimetric analysis (TGA). In the presence of hydrogen peroxide, both dinuclear vanadium dioxido complexes were applied for the oxidation of a series of aromatic and aliphatic alkenes. High catalytic activity and efficiency were achieved using catalysts 1 and 2 in the oxidation of olefins. Alkenes with electron-donating groups make the oxidation processes easy. Thus, in general, aromatic olefins show better substrate conversion in comparison to the aliphatic olefins. Under optimized reaction conditions, both copper catalysts 3 and 4 fail to compete with the activity shown by their vanadium counterparts. Irrespective of olefins, metal (vanadium or copper) complexes of the ligand [salLH4] (I) show better substrate conversion(%) compared with the metal complexes of the ligand [NsalLH4] (II).
