66388-64-5Relevant academic research and scientific papers
Synthesis of Cyclopent-2-enones through Stepwise Cycloaddition of Simple Silyl Enol Ethers and Alk-1-ynes
Yamaguchi, Masahiko,Sehata, Michiru,Hayashi, Akio,Hirama, Masahiro
, p. 1708 - 1709 (1993)
Treatment of silyl enol ethers and alk-1-ynes with SnCl4-Bu3N reagent followed by DBU, leads to cyclopent-2-enones, through cycloaddition reactions; the initial carbon-carbon bond formation is carbometallation of alkynes, and the second step is a base-promoted intramolecular alkylation which reductively eliminates tin species (DBU = 1,8-diazabicycloundec-7-ene).
