7196-01-2

Basic information

• Product Name: Morpholine, 4-(1-phenylethenyl)-
• CAS NO: 7196-01-2
• Molecular Formula: C12H15NO
• Molecular Weight: 189.257
• Mol File: 7196-01-2.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(1-phenylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(1-phenylethenyl)-(7196-01-2)
• EPA Substance Registry System: Morpholine, 4-(1-phenylethenyl)-(7196-01-2)

Safety Data

• Hazardous Substances Data: 7196-01-2(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 536-74-3 phenylacetylene 
• 221130-88-7 4-((Z)-2-Bromo-1-phenyl-vinyl)-morpholine 
• 618-34-8 1-chlorostyrene 
• 98-81-7 1-bromovinylbenzene 
• 1468-28-6 4-benzoylmorpholine 
• 80384-86-7 E-1-morpholino-1-phenyl-2-trimethylsilylethene 
• 50-00-0 formaldehyd 
• 95038-36-1 (α-morpholinobenzyl)diphenylphosphine oxide 
• 98-86-2 acetophenone 

Downstream Products

• 24243-68-3 4-morpholin-4-yl-1,1,4-triphenyl-but-3-en-2-one 
• 101137-59-1 3-morpholinothiocinnamaldehyde 
• 1524-15-8 4,4,4-trifluoro-3-hydroxy-1-phenylbutan-1-one 
• 69857-72-3 ω-(N,N'-Diethoxycarbonyl-hydrazino)-acetophenon 
• 3815-72-3 ω,ω-Bis--acetophenon 
• 5385-58-0 1.3.5.7-Tetraphenyl-anthrachinon 
• 6277-67-4 4-nitro-1,3-diphenyl-butan-1-one 
• 10130-99-1 1-Phenyl-4-<2-nitro-phenyl>-butan-1,3-dion 
• 39655-81-7 (Z)-4-Hydroxy-3-(3-methylene-2,4,5-triphenyl-cyclopenta-1,4-dienyl)-pent-3-en-2-one 
• 6263-83-8 1,5-diphenyl-1,5-pentanedione 
• 6263-84-9 1,3,5-triphenyl-1,5-pentanedione 
• 161029-97-6 2-methoxy-3-nitro-6-phenylpyridine 
• 1799-50-4 4,4,5,5,5-pentafluoro-1-phenyl-pentane-1,3-dione 
• 221130-88-7 4-((Z)-2-Bromo-1-phenyl-vinyl)-morpholine 

Relevant articles and documents

Achieving Aliphatic Amine Addition to Arylalkynes via the Lewis Acid Assisted Triazole-Gold (TA-Au) Catalyst System

Transition metal catalyzed intermolecular hydroamination of the arylalkynes with aliphatic amine is generally problematic due to the good coordination between amine and metal cation. With the combination of 1,2,3-triazole coordinated gold(I) catalyst (TA-Au) and Zn(OTf)2 cocatalyst, this challenging transformation was achieved with good to excellent yields and regioselectivity. Compared to previously reported methods, this approach offered an alternative catalyst system to achieve this fundamental chemical transformation with high efficiency and practical conditions.

Stereoselective Synthesis of a Highly Oxygenated δ-Lactone Related to the Core Structure of (-)-Enterocin

The title compound was prepared in a concise route starting from an appropriately protected (S)-glyceraldehyde. A highly diastereoselective (d.r. >95:5) Mukaiyama aldol reaction of an acetoacetate-derived silyl enol ether served as the initial step of the synthetic sequence. It was found that protection of the glyceraldehyde as a butane-2,3-dione acetal is required to achieve the desired diastereoselectivity. Upon lactonization, a Tsuji-Trost allylation and a subsequent one-pot reaction cascade including an ozonolysis and an α-hydroxylation gave diastereoselective access to the desired α-hydroxy-β-oxo-δ-lactone. Alternative synthetic approaches are discussed and proof for the configuration of the product is presented.

Commercial Supported Gold Nanoparticles Catalyzed Alkyne Hydroamination and Indole Synthesis

Commercial gold nanoparticles supported on titanium dioxide (TiO2) were found to be a highly efficient catalyst for alkyne hydroamination. Terminal alkynes could easily undergo intermolecular hydroamination with low catalyst loadings (0.2 mol% Au) under solvent-free conditions. Indoles were efficiently synthesized using microwave heating through intramolecular hydroamination. (Figure presented.).