6639-01-6

Basic information

• Product Name: 1H-indole-1-propionic acid
• Synonyms: 1H-indole-1-propionic acid
• CAS NO: 6639-01-6
• Molecular Formula: C11H11NO2
• Molecular Weight: 189.21054
• EINECS: 229-643-7
• Mol File: 6639-01-6.mol

Chemical Properties

• Boiling Point: 543.5°C at 760 mmHg
• Flash Point: 204.6°C
• Appearance: /
• Density: 1.323g/cm³
• Vapor Pressure: 7.1E-12mmHg at 25°C
• Refractive Index: 1.799
• CAS DataBase Reference: 1H-indole-1-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-indole-1-propionic acid(6639-01-6)
• EPA Substance Registry System: 1H-indole-1-propionic acid(6639-01-6)

Safety Data

• Hazardous Substances Data: 6639-01-6(Hazardous Substances Data)

Usage

Derivative of indole

Heterocyclic aromatic compound 1H-indole-1-propionic acid is derived from the indole structure, which is an aromatic compound containing a heterocyclic ring (a ring containing more than one type of atom).

Propionic acid moiety

Three-carbon chain with a carboxylic acid functional group The propionic acid part of the molecule consists of a chain with three carbon atoms, and it has a carboxylic acid functional group (-COOH) at one end.

Therapeutic effects

Antioxidant, neuroprotective, and anti-inflammatory properties 1H-indole-1-propionic acid has been found to have potential health benefits, particularly in the field of neuroscience, due to its ability to protect cells from damage caused by free radicals, support the survival and function of nerve cells, and reduce inflammation.

Potential treatment for conditions

Neurodegenerative diseases and psychiatric disorders Research has explored the use of 1H-indole-1-propionic acid in treating various neurological conditions, such as Alzheimer's disease, Parkinson's disease, and psychiatric disorders like depression and schizophrenia.

Precursor to other indole derivatives

Valuable intermediate in organic synthesis 1H-indole-1-propionic acid serves as a starting material or building block for the synthesis of other indole-based compounds, making it an important intermediate in the field of organic chemistry.

InChI:InChI=1/C21H15NO/c23-21-12-10-16-6-3-4-8-19(16)20(21)14-22-18-11-9-15-5-1-2-7-17(15)13-18/h1-14,22H

Upstream product

• 91-59-8 naphthalen-2-ylamine 
• 708-06-5 2-hydroxynaphthalene-1-carbaldehyde 

Downstream Products

• 180984-77-4 9-(2-hydroxynaphthyl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydroxanthene-1,8-dione 

Relevant articles and documents

An easy prepared double naphthalene Schiff-base for highly selective sensing of cyanide via the dipolymer in aqueous solution

A highly selective chemosensor based on an easy-to-prepare double naphthalene Schiff-base (R) is reported for the colorimetric and fluorometric dual-channel sensing of cyanide by taking advantage of the dipolymer in DMSO-H2O (8:2, v/v) HEPES buffer (pH 7.21) solution. The detection of cyanide was carried out via the nucleophilic attack of cyanide anion on the C = O of the probe's tautomer with a 1:1 binding stoichiometry, which could be confirmed by 1H NMR and MS studies. The detection limit of R for the determination of cyanide was estimated to be 8.434 × 10- 9 M. And other anions, including F-, Cl-, Br-, I-, AcO-, and, had nearly no influence on the probing behaviour. The test strips based on R were fabricated, which could act as convenient and efficient CN- test kits.

A highly selective dual-channel Hg2+ chemosensor based on an easy to prepare double naphthalene Schiff base

A non-sulfur chemosensor based on an easy to prepare double naphthalene Schiff base is reported for the colorimetric and fluorometric dual-channel sensing of Hg2+ ions by taking advantage of the twisted intramolecular charge transfer (TICT) mechanism. This work provides a novel approach for the selective recognition of mercury ions. Moreover, this sensor serves as a potential recyclable component in sensing materials and the complex L-Hg2+ (L = 1-[(2-naphthalenylimino)methyl]-2-naphthalenol) can therefore be used as a fluorescent sensor for iodine anions. Notably, the color changes are very significant and all the recognition and recycling processes can be observed by the naked eye.

A double-naphthalene Seaveralkali cyamic radical ion sensor and its synthesis and use (by machine translation)

The invention discloses a double-naphthalene Seaveralkali cyamic radical ion sensor, is using ethanol as solvent, glacial acetic acid as a catalyst, 2 - hydroxy - 1 - angla formaldehyde and β - naphthylamine as the substrate of reaction refluxing reaction, after the reaction cooling, filtering, washing, recrystallization of shall. The sensor can be at room temperature to the cyan ion have very rapid fluorescent intensity response (_AOMARKENCODELTX0AO _ 30s), and with the cyan ion of the response identification is not affected by the interference of the other coexistence anion, to the mercury ion identification of the minimal detection limit has reached 8.434 × 10- 9 M, with high selectivity, high sensitivity and the like, is a collection with very high use value of the cyan ion identification material. The invention also preparing the load the sensor molecule CN- Detection test paper, can be conveniently and quickly cyanide ion detection in water. (by machine translation)