66395-97-9Relevant academic research and scientific papers
A FACILE SYNTHESIS OF 4-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINES: A TOTAL SYNTHESIS OF (+/-)-CHERYLLINE
Hara, Hiroshi,Shirai, Ryuichi,Hoshino, Osamu,Umezawa, Bunsuke
, p. 1945 - 1950 (2007/10/02)
Reaction of benzylamines (3a-d) and styrene oxide at 140 deg C gave quantitavely β-hydroxyphenethylamine (2a-d), acid treatment of which afforded 4-aryl-1,2,3,4-tetrahydroisoquinolines (8a-d) in high yields.On the other hand, the styrene oxide (10 or 15)
