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2-(4-methoxyphenyl)oxirane, also known as p-methoxyphenyl glycidyl ether, is a chemical compound that belongs to the family of epoxy ethers. It is a colorless liquid with a slightly sweet odor, insoluble in water but soluble in organic solvents. This versatile building block in organic chemistry is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds.

6388-72-3

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6388-72-3 Usage

Uses

Used in Pharmaceutical Industry:
2-(4-methoxyphenyl)oxirane is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
2-(4-methoxyphenyl)oxirane is used as a precursor in the production of agrochemicals, aiding in the creation of effective pesticides and other agricultural chemicals.
Used in Organic Synthesis:
2-(4-methoxyphenyl)oxirane is used as a valuable and important compound in the field of organic synthesis, due to its reactivity and ability to undergo various chemical reactions.
Used in Resin Production:
2-(4-methoxyphenyl)oxirane is used as a raw material in the production of resins, contributing to the manufacturing of durable and versatile polymeric materials.
Used in Adhesives and Coatings Industry:
2-(4-methoxyphenyl)oxirane is used as a component in the formulation of adhesives and coatings, enhancing their performance and application in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 6388-72-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,8 and 8 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6388-72:
(6*6)+(5*3)+(4*8)+(3*8)+(2*7)+(1*2)=123
123 % 10 = 3
So 6388-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O2/c1-10-8-4-2-7(3-5-8)9-6-11-9/h2-5,9H,6H2,1H3

6388-72-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-methoxyphenyl)oxirane

1.2 Other means of identification

Product number -
Other names 4-Methoxyphenyloxirane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6388-72-3 SDS

6388-72-3Relevant academic research and scientific papers

Singly Unified Driving Force Dependence of Outer-Sphere Electron-Transfer Pathways of Nonheme Manganese(IV)-Oxo Complexes in the Absence and Presence of Lewis Acids

Sharma, Namita,Lee, Yong-Min,Li, Xiao-Xi,Nam, Wonwoo,Fukuzumi, Shunichi

, p. 13761 - 13765 (2019)

Epoxidation of styrene derivatives, sulfoxidation of thioanisole derivatives, and hydroxylation of toluene derivatives by a nonheme manganese(IV)-oxo complex binding triflic acid, [(N4Py)MnIV(O)]2+-(HOTf)2 [1-(H+/sup

Characterization and catalytic property of manganese(III) complexes with Schiff bases

Li,Zhang

, p. 1166 - 1172 (2015)

Two mononuclear manganese(III) complexes, [MnL1(OH2)(CH3OH)]·ClO4 (1) and [MnL2] (2), where L1 and L2 are the deprotonated forms of N,N′-bis(5-chloro-2-hydroxybenzylidene)ethane-

Tris{2-[(5-fluorosalicylidene)amino]ethyl}amine and its manganese(iii) complex: Synthesis, characterization, crystal structures, and catalytic property

Wei, Fen-Yan

, p. 603 - 607 (2017)

A tris-Schiff base tris{2-[(5-fluorosalicylidene)amino]ethyl}amine (H3L) was prepared by the reaction of 1:3 molar ratio of tris(2-aminoethy1)amine with 5-fluorosalicylaldehyde in methanol. The Schiff base reacted with manganese perchlorate to

Synthesis, structures, and catalytic property of manganese(III) complexes derived from N,N′-bis(5-fluoro-2-hydroxybenzylidene)ethane-1,2-diamine

Li,Zhang

, p. 142 - 148 (2015)

Two mononuclear manganese(III) complexes, [Mn(L)(NCS)] (I) and [Mn(L)(OH2)2] · Hfac · H2O (II), where L is the deprotonated form of N,N′-bis(5-fluoro-2-hydroxybenzylidene)ethane-1,2-diamine, Hfac is hexafluoroacetylacetona

Synthesis, characterization, and catalytic activity of supported molybdenum Schiff base complex as a magnetically recoverable nanocatalyst in epoxidation reaction

Moradi-Shoeili, Zeinab,Zare, Maryam,Bagherzadeh, Mojtaba,Ozkar, Saim,Akbayrak, Serdar

, p. 668 - 677 (2016)

A heterogeneous nanocatalyst was prepared via covalent anchoring of dioxomolybdenum(VI) Schiff base complex on core-shell structured Fe3O4@SiO2. The properties and the nature of the surface-fixed complex have been identifi

Aerobic oxidation of olefins in the presence of a new amine functionalized core–shell magnetic nanocatalyst

Rayati, Saeed,Nejabat, Fatemeh,Panjiali, Fatemeh

, p. 52 - 57 (2019)

In this study meso-tetrakis(4-carboxyphenyl)porphyrinatomanganese(III) acetate was immobilized onto the surface of amine functionalized Fe3O4 magnetic nanoparticles through covalent linkage. The new magnetic nanocatalyst [Fe3/s

MeOTf/KI-catalyzed efficient synthesis of 2-arylnaphthalenesviacyclodimerization of styrene oxides

Chen, Chao,Xi, Chanjuan,Zhang, Zeyu,Zou, Song

supporting information, p. 8559 - 8565 (2021/10/20)

The MeOTf/KI-catalyzed synthesis of 2-arylnaphthalene derivatives from aryl ethylene oxides in alcohol under ambient conditions is described. The present protocol has a higher atom efficiency and wider substrate applicability with excellent yields. The reaction proceeded using the aryl ethylene oxides to give 2-arylnaphthalenes either in homo-coupling or in cross-coupling. The reaction could also be carried out at the gram scale in minutes.

Aldehyde-catalyzed epoxidation of unactivated alkenes with aqueous hydrogen peroxide

Kokotos, Christoforos G.,Kokotou, Maroula G.,Lotter, Dominik,Sparr, Christof,Triandafillidi, Ierasia

, p. 10191 - 10196 (2021/08/12)

The organocatalytic epoxidation of unactivated alkenes using aqueous hydrogen peroxide provides various indispensable products and intermediates in a sustainable manner. While formyl functionalities typically undergo irreversible oxidations when activating an oxidant, an atropisomeric two-axis aldehyde capable of catalytic turnover was identified for high-yielding epoxidations of cyclic and acyclic alkenes. The relative configuration of the stereogenic axes of the catalyst and the resulting proximity of the aldehyde and backbone residues resulted in high catalytic efficiencies. Mechanistic studies support a non-radical alkene oxidation by an aldehyde-derived dioxirane intermediate generated from hydrogen peroxide through the Payne and Criegee intermediates.

Rate-Limiting Step of Epoxidation Reaction of the Oxoiron(IV) Porphyrin π-Cation Radical Complex: Electron Transfer Coupled Bond Formation Mechanism

Fujii, Hiroshi,Hada, Masahiko,Ishimizu, Yuri,Ma, Zhifeng

supporting information, p. 17687 - 17698 (2021/12/01)

Epoxidation reactions catalyzed by high-valent metal-oxo species are key reactions in various biological and chemical processes. Because the redox potentials of alkenes are higher than those of most high-valent metal-oxo species, the electron transfer (ET

Substituent effects in dioxovanadium(V) schiff-base complexes: Tuning the outcomes of oxidation reactions

McCaffrey, Vanessa P.,Conover, Olivia Q.,Bernard, Michael A.,Yarranton, Jonathan T.,Lessnau, Nicholas R.,Hempfling, Jordan P.

, (2021/06/21)

Dioxovanadium(V) salicylaldehyde semicarbazone complexes with substituents on the ligand that span the range of electron donating (methoxy) to electron withdrawing (nitro) have been synthesized and characterized by NMR, IR, CV and EPR. The reactivity of these complexes toward the oxidation of styrene (as compared to the proteo complex and vanadyl acetylacetonate) has been studied in the presence of two different oxidants (hydrogen peroxide and tert-butyl hydrogen peroxide, TBHP). The complexes have been shown to exhibit different selectivity towards epoxidation versus oxidative cleavage based on the substitution of the ligand and the oxidant chosen. Epoxidation is favored with the methoxy substituted complex in the presence of hydrogen peroxide, while oxidative cleavage is the preferred reaction pathway for the nitro substituted complex with hydrogen peroxide. Conversions for these reaction are comparable to similar catalysts but with improved selectivity.

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