664-66-4

Usage

Uses

Used in Pharmaceutical Industry:
2,2,3-Trifluoro-succinic acid serves as a chemical intermediate, playing a crucial role in the synthesis of various pharmaceuticals. Its unique properties, including the presence of fluorine atoms, contribute to the development of new drugs with enhanced efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical sector, 2,2,3-Trifluoro-succinic acid is utilized as a building block for the production of agrochemicals, helping to create compounds with improved pesticidal properties and environmental compatibility.
Used in Specialty Chemicals and Materials Production:
Beyond its applications in pharmaceuticals and agrochemicals, 2,2,3-Trifluoro-succinic acid also acts as a key component in the synthesis of specialty chemicals and materials. Its incorporation into these products can lead to advancements in various industrial applications, such as coatings, polymers, and other high-performance materials.

Upstream product

• 866-16-0 chloro-trifluoro-succinic acid 
• 108-31-6 maleic anhydride 

Downstream Products

• 685-64-3 difluoromaleic acid 
• 2714-32-1 difluorofumaric acid 
• 758-68-9 trifluoro-succinic acid diethyl ester 
• 669-78-3 difluoromaleic anhydride 

Relevant academic research and scientific papers

Molecular structure of 3,4-difluorofuran-2,5-dione (difluoromaleic anhydride) as determined by electron diffraction and microwave spectroscopy in the gas phase and by theoretical computations

The structure of 3,4-difluorofuran-2,5-dione has been determined experimentally in the gas phase by microwave spectroscopy using rotation constants derived from five isotopomers and by a combined analysis of electrondiffraction and microwave data. The geometry is planar with C2v symmetry. Structural parameters [distances (rαo)/pm, angles a/deg, (1α errors)] for the combined analysis are: r(C=O) = 119.0(1); r(C-F) = 130.9(2); r(C=C) = 133.2(3); r(O-C) = 139.3(1); KC-C) = 148.5(2); C-C=C = 108.3(1); ZC=C-F = 129.9-(1); C-C=O = 129.3(1); C-O-C = 108.9(1); O-C-C = 107.2(1). These values are in excellent agreement with those obtained in an ab initio study of the molecular geometry at the MP2/6-311+G (2df) level of theory. The dipole moment of difluoromaleic anhydride has been determined experimentally by Starkeffect measurements to be 1.867(3) D.

Dihydropyridazinones, pyridazinones and related compounds as fungicides

This invention relates to substituted dihydropyridazinones, pyridazinones and related compounds, of the formula STR1 wherein A, Q, D and R1 are as defined within, compositions containing these compounds and methods of controlling agricultural and mammalian fungal diseases.

The formation of halogenated succinates by liquid-phase direct fluorination with elemental fluorine

Direct fluorination of maleic anhydride with elemental fluorine has been investigated in different solvents at low temperatures.It was discovered that the net conversion of maleic anhydride, as well as the overall yield and composition of the halogenated products, depend strongly on the experimental conditions employed.Fluorinations conducted in fluorotrichloromethane, chloroform or mixtures thereof, in the presence of sodium fluoride, resulted in good yields of halogenated succinic acid derivatives: the predominant products being 2,3-dihalogenated succinic acids.Product distributions varied widely between experiments conducted at 0 deg C and -25 deg C, and also between experiments conducted in neat CHCl3 and in CFCl3/CHCl3 mixtures.Experimental details and some comments regarding the stereoselectivity of halogen addition are provided.