6640-08-0 Usage
Functionality
Immunosuppressive drug
Mechanism of Action
Inhibits dihydroorotate dehydrogenase enzyme
Involvement in Metabolic Pathway
De novo pyrimidine synthesis pathway
Effect on T-cells
Suppresses T-cell activation and proliferation
Clinical Applications
Preventing transplant rejection, treating autoimmune diseases
Potential Anti-cancer Properties
Under investigation, as de novo pyrimidine synthesis pathway is often upregulated in cancer cells
Further Research
Required to fully understand its anticancer effects and potential use in cancer therapy
Check Digit Verification of cas no
The CAS Registry Mumber 6640-08-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,4 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6640-08:
(6*6)+(5*6)+(4*4)+(3*0)+(2*0)+(1*8)=90
90 % 10 = 0
So 6640-08-0 is a valid CAS Registry Number.
6640-08-0Relevant academic research and scientific papers
Improved synthesis of N1-substituted orotic acid derivatives
Senger, Nicholas A.,Bowler, Jeannette T.,Mercado, Rene S.,Lin, Sidney,Wu, Weiming
, p. 4245 - 4246 (2013/07/26)
An improved method for the synthesis of N1-substituted orotic acid derivatives is reported. The method involves sequential incorporation of nitrogen atoms to the pyrimidine structure from simple starting materials and thus allows the synthesis of N1-subst
