6641-03-8

Basic information

• Product Name: 4-chloro-2,6-bis(chloromethyl)phenol
• CAS NO: 6641-03-8
• Molecular Formula: C₈H₇Cl₃O
• Molecular Weight: 225.4996
• Mol File: 6641-03-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 332.2°C at 760 mmHg
• Flash Point: 154.7°C
• Density: 1.452g/cm³
• Vapor Pressure: 7.67E-05mmHg at 25°C
• Refractive Index: 1.592
• CAS DataBase Reference: 4-chloro-2,6-bis(chloromethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-2,6-bis(chloromethyl)phenol(6641-03-8)
• EPA Substance Registry System: 4-chloro-2,6-bis(chloromethyl)phenol(6641-03-8)

Safety Data

• Hazardous Substances Data: 6641-03-8(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 17026-49-2 4-chloro-2,6-bis(hydroxymethyl)phenol 

Downstream Products

• 6642-07-5 4-chloro-2,6-bis(5-chloro-2-hydroxybenzyl)phenol 
• 71642-94-9 2,6-Bis(5-chloro-2-hydroxy-3-nitrobenzyl)-4-chlorophenol 
• 857974-96-0 4-chloro-2,6-bis-(3,5-dibromo-4-hydroxy-benzyl)-phenol 

Relevant articles and documents

Magnetic and structural properties of dinuclear singly bridged-phenoxido metal(II) complexes

The reaction of a methanolic solution containing the bi-compartmental phenolic ligand 2,6-bis[bis(2-pyridylmethyl)aminomethyl]-4-chlorophenol (LCl-OH) with MCl2·nH2O in the presence of NH4PF6 or NaClO4 afforded the dinuclear bridged-phenoxido dichlorido-metal(ii) complexes [Co2(μ-LClO)(H2O)2Cl2][Co2(μ-LClO)(MeOH)2Cl2](PF6)2 (1), [Ni2(μ-LClO)(MeOH)2Cl2]PF6 (2), [Ni2(μ-LClO)(MeOH)(H2O)Cl2]ClO4·1.25H2O (3), [Cu2(μ-LClO)Cl2]PF6·1/2MeOH (4) and [Zn2(μ-LClO)Cl2]PF6·MeOH (5). The complexes were characterized by elemental microanalyses, conductivity measurements, IR and UV-Vis spectroscopy, mass spectrometry and single crystal X-ray crystallography. Each M(ii) center within the dinuclear complex cations is octahedrally coordinated in complexes 1-3, and five-coordinated distorted square pyramidal in 4 and 5. Magnetic susceptibility measurements at variable temperature of the complexes 1-4 revealed weak to moderate antiferromagnetic coupling with |J| values = 8.38, 39.0, 30.2 and 0.79 cm-1, respectively. The results of DFT calculations correlate well with the experimentally determined antiferromagnetic coupling and show that the magnetic exchange coupling occurs mainly through the phenoxido bridge M-O-M. Implications of geometry around the central metal ion, M...M distance, M-O-M bond angle and overlapping of magnetic orbitals on the magnetic exchange coupling are discussed.