66421-39-4

Basic information

• Product Name: 1H-Pyrazolo[3,4-d]pyrimidine, 4-[(4-methylphenyl)sulfonyl]-1-phenyl-
• CAS NO: 66421-39-4
• Molecular Formula: C18H14N4O2S
• Molecular Weight: 350.401
• Mol File: 66421-39-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-d]pyrimidine, 4-[(4-methylphenyl)sulfonyl]-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-d]pyrimidine, 4-[(4-methylphenyl)sulfonyl]-1-phenyl-(66421-39-4)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-d]pyrimidine, 4-[(4-methylphenyl)sulfonyl]-1-phenyl-(66421-39-4)

Safety Data

• Hazardous Substances Data: 66421-39-4(Hazardous Substances Data)

Upstream product

• 6014-07-9 4-mercapto-1-phenyl-1H-pyrazolo<3,4-d>pyrimidine 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 5334-48-5 4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine 

Downstream Products

• 59563-84-7 phenyl-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 
• 59563-87-0 (4-methoxy-phenyl)-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 
• 89549-55-3 (4-Fluoro-phenyl)-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 

Relevant articles and documents

Electrophilic cyanations. I. Synthesis of thiocyanato-heteroarenes and tosylheteroarenes from mercapto-heteroarenes using p-toluenesulfonyl cyanide

Mercaptoheteroarenes (1) underwent electrophilic cyanation with p-toluenesulfonyl cyanide (TsCN) in THF in the presence of NaH to give the corresponding thiocyanatoheteroarenes (2) in moderate to good yields. In DMF, tosylheteroarenes (4) were formed by substitution with p-toluenesulfinate ion through thiocyanatoheteroarenes (2).