664326-40-3Relevant academic research and scientific papers
The reactions of copper-dibromodifluoromethane-amide systems with alcohols
Clark, James H.,McClinton, Martin A.,Blade, Robert J.
, p. 257 - 267 (1992)
1,1,1-Trifluoro-2-arylethanes can be prepared by the trifluoromethyldehydroxylation of benzyl alcohols using the copper-dibromodifluoromethane-amide reaction system, although the yields are low.The mechanism of the reaction may involve chelation of the substrate to copper so that α-substituted benzyl alcohols and other alcohols are unreactive.
A NEW METHOD OF FLUOROALKYLATION BY A WITTIG REACTION
Escoula, B.,Rico, I.,Laval, J. P.,Lattes, A.
, p. 35 - 38 (2007/10/02)
A new method has been developed for the introduction of a perfluorinated chain into an hydrogenated moiety.It is based on the use of a new fluorinated reagent, (C6H5)3P+-CH2CH2RF I- which couple to a non fluorinated aldehyde RH-C(O)H in a Wittig reaction.
