66433-20-3Relevant academic research and scientific papers
THE REACTION OF 2-CHLORO-4-METHYLTHIOQUINAZOLINE WITH ALKYLAMINES IN DIMETHYLFORMAMIDE
Miki, Hideki,Yamada, Junji
, p. 11 - 13 (2007/10/02)
The reaction of 2-chloro-4-methylthioquinazoline with alkylamines in dimethylformamide afforded 2,4-bis(methylthio)-2-alkylamino-4-methylthio-, 4-alkylamino-2-chloro, 4-alkylamino-2-methylthio-, and 2,4-bis(alkylamino)quinazoline.The relative easiness of displacement of the chlorine and/or the methylthio group in 2-chloro-4-methylthioquinazoline depended on the bulkiness of alkylamines.
