66433-94-1Relevant academic research and scientific papers
Strategies to reduce hERG K+ channel blockade. Exploring heteroaromaticity and rigidity in novel pyridine analogues of dofetilide
Carvalho, Jo?o F. S.,Louvel, Julien,Doornbos, Maarten L. J.,Klaasse, Elisabeth,Yu, Zhiyi,Brussee, Johannes,Ijzerman, Adriaan P.
supporting information, p. 2828 - 2840 (2013/05/22)
Drug-induced blockade of the human ether-a-go-go-related gene K+ channel (hERG) represents one of the major antitarget concerns in pharmaceutical industry. SAR studies of this ion channel have shed light on the structural requirements for hERG
Synthesis and characterization of new aromatic tweezers and complex formation with tropylium ion in 1,2-dichloroethane
Laemsae, Markku,Kiviniemi, Sari,Kettukangas, Eeva-Riitta,Nissinen, Maija,Pursiainen, Jouni,Rissanen, Kari
, p. 551 - 558 (2007/10/03)
A series of benzene and pyridine tweezers bearing phenyl, naphthyl and anthryl receptor units was prepared and characterized. The x-ray crystal structure of the 1,3-bis(9-methanolanthracene)methylbenzene ligand (5) is reported. UV-visible and NMR spectros
INTERACTION OF 2,6-BIS(ARYLOXYMETHYL)PYRIDINES WITH AEROSIL SURFACE
Kamalov, G. L.,Zakolodyazhnaya, O. V.,Manolova, A. V.,Gavsevich, Yu. V.
, p. 561 - 566 (2007/10/02)
Monolayer adsorption of 2,6-bis(aryloxymethyl)pyridines from benzene solutions by Aerosil is characterized by weak intermolecular interaction of the sorbates, so that it is possible to apply acid-base concepts in interpreting the interaction of the compou
