66433-94-1Relevant articles and documents
Strategies to reduce hERG K+ channel blockade. Exploring heteroaromaticity and rigidity in novel pyridine analogues of dofetilide
Carvalho, Jo?o F. S.,Louvel, Julien,Doornbos, Maarten L. J.,Klaasse, Elisabeth,Yu, Zhiyi,Brussee, Johannes,Ijzerman, Adriaan P.
supporting information, p. 2828 - 2840 (2013/05/22)
Drug-induced blockade of the human ether-a-go-go-related gene K+ channel (hERG) represents one of the major antitarget concerns in pharmaceutical industry. SAR studies of this ion channel have shed light on the structural requirements for hERG
INTERACTION OF 2,6-BIS(ARYLOXYMETHYL)PYRIDINES WITH AEROSIL SURFACE
Kamalov, G. L.,Zakolodyazhnaya, O. V.,Manolova, A. V.,Gavsevich, Yu. V.
, p. 561 - 566 (2007/10/02)
Monolayer adsorption of 2,6-bis(aryloxymethyl)pyridines from benzene solutions by Aerosil is characterized by weak intermolecular interaction of the sorbates, so that it is possible to apply acid-base concepts in interpreting the interaction of the compou