Glycin-2,4,6-trimethylbenzylester, also known as Gly-OTMB, is a chemical compound derived from glycine, an amino acid, and 2,4,6-trimethylbenzyl alcohol. It is a white crystalline solid that is soluble in organic solvents. Gly-OTMB is often used as a protecting group in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). The trimethylbenzyl group provides a stable and easily removable protecting group for the amino group of glycine, allowing for the controlled addition of amino acids during peptide synthesis. The compound is also used as a reagent in various chemical reactions and as a building block in the synthesis of more complex organic molecules. Its stability and ease of removal make it a valuable tool in the field of organic chemistry and peptide chemistry.
6645-08-5
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Basic information
- Product Name: Glycin-2,4,6-trimethylbenzylester; Gly-OTMB
- Synonyms: Glycin-2,4,6-trimethylbenzylester; Gly-OTMB
- CAS NO:6645-08-5
- Molecular Formula:
- Molecular Weight: 243.733
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Glycin-2,4,6-trimethylbenzylester; Gly-OTMB(CAS DataBase Reference)
- NIST Chemistry Reference: Glycin-2,4,6-trimethylbenzylester; Gly-OTMB(6645-08-5)
- EPA Substance Registry System: Glycin-2,4,6-trimethylbenzylester; Gly-OTMB(6645-08-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 6645-08-5(Hazardous Substances Data)
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6645-08-5 Usage
Check Digit Verification of cas no
The CAS Registry Mumber 6645-08-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,4 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.Calculate Digit Verification of CAS Registry Number 6645-08:
(6*6)+(5*6)+(4*4)+(3*5)+(2*0)+(1*8)=105
105 % 10 = 5
So 6645-08-5 is a valid CAS Registry Number.
6645-08-5Upstream product
6645-08-5Downstream Products
- 33200-63-4 {2-[(2-Carbamoyl-ethyl)-(2-nitro-phenylsulfanyl)-amino]-acetylamino}-acetic acid 2,4,6-trimethyl-benzyl ester
- 33096-25-2 {2-[(2-Cyano-ethyl)-(2-nitro-phenylsulfanyl)-amino]-acetylamino}-acetic acid 2,4,6-trimethyl-benzyl ester
- 33096-24-1 Z-(C2H4CN)Gly-Gly-OTMB
- 80971-70-6 1-(benzyloxycarbonylglycyl)aminocyclopropane-1-carbonylglycine 2,4,6-trimethylbenzyl ester
- 88744-40-5 Pab-Gly-OTmb
- 88744-39-2 Ant-Gly-OTmb
- 80977-02-2 1-(t-butyloxycarbonyl-O-acetyl-L-tyrosyl)aminocyclopropane-1-carbonylglycine 2,4,6-trimethylbenzyl ester
- 35048-68-1 NPS-γ-2,4,6-trimethylbenzyl-L-glutamylglycin-OTMB; NPS-Glu(OTMB)-Gly-OTMB
- 35048-67-0 NPS-γ-benzyl-L-glutamylglycin-OTMB; NPS-Glu(OBzl)-Gly-OTMB
- 33096-27-4 NPS-(C2H4CN)Gly-Gly-Gly-OTMB
- 33203-43-9 {2-[((S)-2-Benzyloxycarbonylamino-propionyl)-(2-carbamoyl-ethyl)-amino]-acetylamino}-acetic acid 2,4,6-trimethyl-benzyl ester
- 73994-82-8 benzyloxycarbonylglycyl-2-methylalanylglycine 2,4,6-trimethylbenzyl ester
- 73994-85-1 benzyloxycarbonylglycylglycylglycine 2,4,6-trimethylbenzyl ester
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Glycin-2,4,6-trimethylbenzylester; Gly-OTMB
