66464-25-3

Basic information

• Product Name: 4,4-dimethyl-2-(2-(thiophene-2-yl)phenyl)-4,5-dihydrooxazole
• Synonyms: 4,4-dimethyl-2-(2-(thiophene-2-yl)phenyl)-4,5-dihydrooxazole
• CAS NO: 66464-25-3
• Molecular Weight: 257.356
• Mol File: 66464-25-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,4-dimethyl-2-(2-(thiophene-2-yl)phenyl)-4,5-dihydrooxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-dimethyl-2-(2-(thiophene-2-yl)phenyl)-4,5-dihydrooxazole(66464-25-3)
• EPA Substance Registry System: 4,4-dimethyl-2-(2-(thiophene-2-yl)phenyl)-4,5-dihydrooxazole(66464-25-3)

Safety Data

• Hazardous Substances Data: 66464-25-3(Hazardous Substances Data)

Upstream product

• 2786-07-4 2-thienyl lithium 
• 66464-20-8 2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 
• 445-29-4 o-fluoro-benzoic acid 
• 1003-09-4 2-bromothiophene 
• 1190302-19-2 C₁₁H₁₄BNO₃ 
• 66195-42-4 2-(2-iodophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 

Relevant articles and documents

Unified Protocol for Cobalt-Catalyzed Oxidative Assembly of Two Aryl Metal Reagents Using Oxygen as an Oxidant

The first cobalt-catalyzed oxidative cross-coupling reaction of two aryl metal reagents is described. An equivalent amount of two aryl Grignard or lithium reagents, after mediation by an equivalent amount of simple ClTi(OEt)3, was facilely assembled under the catalysis of 1 mol % of CoCl2/10 mol % of DMPU using oxygen. The cross-couplings between various aryl metal reagents, especially between two structurally similar aryl Grignard reagents, proceeded smoothly and selectively and, thus, provided a highly general and efficient method for the construction of biaryl compounds.