665-46-3

Basic information

• Product Name: Tetraethylammonium fluoride dihydrate
• Synonyms: TETRAETHYLAMMONIUM FLUORIDE;Tetraethylammonium fluoride dihydrate;N,N,N-TRIETHYL-ETHANAMINIUFLUORIDE;Ethanaminium, N,N,N-triethyl-, fluoride;Tetraethylazanium fluoride;N,N,N-Triethylethanaminium·fluoride;Tetraethylaminium·fluoride;TetraethylaMMoniuM Fluoride
• CAS NO: 665-46-3
• Molecular Formula: C₈H₂₀N*F
• Molecular Weight: 185.28
• EINECS: 211-559-7
• Product Categories: quarternary ammonium salts;Ammonium Fluorides (Quaternary);Quaternary Ammonium Compounds
• Mol File: 665-46-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 80 °C (decomp)
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Tetraethylammonium fluoride dihydrate(CAS DataBase Reference)
• NIST Chemistry Reference: Tetraethylammonium fluoride dihydrate(665-46-3)
• EPA Substance Registry System: Tetraethylammonium fluoride dihydrate(665-46-3)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 3-9
• Hazardous Substances Data: 665-46-3(Hazardous Substances Data)

Usage

Uses

Tetraethylammonium Fluoride Dihydrate is an analog of Tetraethylammonium Chloride (T292700). Tetraethylammonium Chloride can be used as a source of tetraethylammonium ions for various pharmaceutical studies and has the ability to block K+ channels in various tissues. Tetraethylammonium Chloride can also block the transmission of nervous impulses across autonomic ganglions.

InChI:InChI=1/C8H20N.FH.2H2O/c1-5-9(6-2,7-3)8-4;;;/h5-8H2,1-4H3;1H;2*1H2/q+1;;;/p-1

Upstream product

• 68-05-3 tetraethylammonium iodide 
• 7732-18-5 water 
• 71-91-0 tetraethylammonium bromide 
• 56-34-8 tetraethylammonium chloride 
• 77-98-5 tetraethylammonium hydroxide 

Downstream Products

• 17351-61-0 tetraethylammonium bicarbonate 
• 1351532-94-9 [Ir(2-(2-benzothienyl)pyridinato-C₂,N)2(OOCC₆H₄B(C₆H₂(CH₃)3)2)][tetraethylammonium] 
• 954271-75-1 [(1R,2S)-1-(2-amino-benzenesulfonylaminocarbonyl)-2-vinyl-cyclopropyl]-carbamic acid tert-butyl ester 
• 1172604-59-9 [CuF(tris(2-(2-(4-nitrobenzyl)phenylamino)ethyl)amine)]BF₄ 
• 14683-12-6 tellurium 

Relevant articles and documents

Unraveling the cation and anion effects and kinetics for ionic liquid catalyzed direct synthesis of methyl acrylate under mild conditions

The direct synthesis of methyl acrylate (MA) from methyl acetate and trioxane at 350-380 °C is regarded as a supplementary route for the industrial propylene oxidation process; however, it suffers from rapid catalyst deactivation. Herein, a novel ionic liquid catalyzed mild liquid-phase system was developed for the direct synthesis of MA from methyl acetate and trioxane, where N,O-bis(trimethylsilyl)acetamide (BSA) was used as a probase for α-deprotonation and enol silyl etherification of methyl acetate. The trioxane decomposition to formaldehyde and methyl acetate enolization to 1-methoxy-1-trimethylsilyloxyethene proceeded with the catalysis of [Cation]Cl/MClx (M = Cu+, Fe3+, Zn2+ and Al3+) and [Cation]F, respectively. The cations and anions were observed to have significant effects on the yield and selectivity of MA, owing to the steric hindrance, acid site category and strength confirmed by pyridine probing FT-IR characterization. As a result, up to 60.2% yield with 94.6% selectivity of MA could be achieved when [N3,3,3,3]F and [N3,3,3,3]Cl/AlCl3 with 67 mol% AlCl3 were used in the presence of BSA at 25 °C. Kinetic studies indicated that the trioxane decomposition with the activation barrier of 41.2 ± 0.3 kJ mol-1 was the rate-determining step.

Synthesis of Quaternary Ammonium Fluoride Salts by a Solid-Liquid Halogen Exchange Process in Protic Solvents

Both hydrophilic and lipophilic quaternary ammomium fluoride compounds are prepared by direct exchange of the corresponding halides with solid potasium fluoride containing an optimized amount of water (4.0 mol percent).The procedure is most effective when methanol is applied as a solvent.A variety of quaternary ammonium fluorides were prepared in 75-97percent yield.

Tetraethylammoniumtrithiomonofluorophosphat

-