66504-57-2Relevant academic research and scientific papers
Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides
Manley-King, Clarina I.,Terre'Blanche, Gisella,Castagnoli Jr., Neal,Bergh, Jacobus J.,Petzer, Jacobus P.
experimental part, p. 3104 - 3110 (2009/09/05)
Based on a recent report that 1-methyl-3-phenylpyrrolyl analogues are moderately potent reversible inhibitors of the enzyme monoamine oxidase B (MAO-B), a series of structurally related N-methyl-2-phenylmaleimidyl analogues has been prepared and evaluated
3a-(substituted phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles for treating depression in warm-blooded animals
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, (2008/06/13)
This disclosure describes 3a-(substituted-phenyl)-2,3,3a,4,7,7a-hexahydro[or 3a-(substituted-phenyl)octahydro]-4,7-alkano-1H-isoindoles which possess activity as antidepressants and as antistress agents in mammals.
5-Aryl-3-azabicycloheptan-6-one Ketals, Compounds with Morphine-Like Analgesic Activity
McKenzie, Thomas C.,Epstein, Joseph W.,Fanshawe, William J.,Dixon, J. Scott,Osterberg, Arnold C.,et al.
, p. 628 - 632 (2007/10/02)
A series of 5-aryl-3-azabicycloheptan-6-one ketals 6 were synthesized by hydride reduction of 1-aryl-4,4-dimethoxy-1,2-cyclobutanedicarboximides 5.Imides 5 were obtained as the sole, regioselective products of the photocycloaddition of 1,1-
Diels-Alder Dimerization of 2-Arylmaleimides. X-Ray Crystal Structure of the Dimer of 2-p-Tolylmaleimide
Epstein, Joseph W.,McKenzie, Thomas C.,Lovell, M. F.,Perkinson, Nancy A.
, p. 314 - 315 (2007/10/02)
Dimers (4) and (7) were obtained during the course of the Meerwein arylation reaction; a Diels-Alder reaction is proposed for the mechanism of the dimerization, and the X-ray structure of (4) is reported.
