66529-34-8

Upstream product

• 24965-94-4 (3R,1R)-3-methylcyclohexanol 
• 124-63-0 methanesulfonyl chloride 
• 591-23-1 m-methylcyclohexanol 

Downstream Products

• 1346161-64-5 N-(1-methyl-1H-pyrazol-4-yl)-1-(3-methylcyclohexyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine 
• 66529-35-9 (1S,3R)-3-Methyl(1-2H₁)cyclohexane 

Relevant academic research and scientific papers

PYRAZOLE COMPOUNDS AS JAK INHIBITORS

The present invention relates to compounds of formula (I), wherein R1, R2, R1a, R1b have the meaning as cited in the description and the claims. Said compounds are useful as JAK inhibitors for the treatment or prophylaxis of immunological, inflammatory, autoimmune, allergic disorders, and immunologically-mediated diseases. The invention also relates to pharmaceutical compositions including said compounds, the preparation of such compounds as well as the use as medicaments.

Optical Rotatory Dispersion Studies. 133. Deuterium Octant Contributions in Cyclohexanones

The synthesis of four conformationally rigid monodeuterium-substituted cyclohexanones, (2R,4R)-4-isopropyl(2-2H1)cyclohexanone (1), (2S,4R)-4-isopropyl(2-2H1)cyclohexanone (2), (3R,4R)-4-tert-butyl(3-2H1)-cyclohexanone (3), and (3S,4R)-4-tert-butyl(3-2H1)