66548-88-7

Basic information

• Product Name: PYRIDAZINE, 3-CHLORO-6-[4-(TRIFLUOROMETHYL)PHENYL]-
• Synonyms: AKOS AKM01237;PYRIDAZINE, 3-CHLORO-6-[4-(TRIFLUOROMETHYL)PHENYL]-;3-chloro-6-[4-(trifluoromethyl)phenyl]pyridazine
• CAS NO: 66548-88-7
• Molecular Formula: C₁₁H₆ClF₃N₂
• Molecular Weight: 258.63
• Mol File: 66548-88-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: PYRIDAZINE, 3-CHLORO-6-[4-(TRIFLUOROMETHYL)PHENYL]-(CAS DataBase Reference)
• NIST Chemistry Reference: PYRIDAZINE, 3-CHLORO-6-[4-(TRIFLUOROMETHYL)PHENYL]-(66548-88-7)
• EPA Substance Registry System: PYRIDAZINE, 3-CHLORO-6-[4-(TRIFLUOROMETHYL)PHENYL]-(66548-88-7)

Safety Data

• Hazardous Substances Data: 66548-88-7(Hazardous Substances Data)

Upstream product

• 135034-10-5 3-chloro-6-iodopyridazine 
• 109541-76-6 tris(4-(trifluoromethyl)phenyl)bismuthane 

Downstream Products

• 66549-38-0 3-ethyl-6-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine 
• 66548-84-3 6-(4-trifluoromethyl-phenyl)-[1,2,4]triazolo[4,3-b]pyridazine 
• 66548-89-8 3-methyl-6-(α,α,α-trifluoro-p-tolyl)-1,2,4-triazolo[4,3-b]-pyridazine 
• 634922-09-1 (R)-2-[6-(4-trifluoromethyl-phenyl)-pyridazin-3-yl]-octahydro-pyrido[1,2-a]pyrazine 

Relevant articles and documents

Pd-catalyzed chemoselective cross-coupling reaction of triaryl- or triheteroarylbismuth compounds with 3,6-dihalopyridazines

The cross-coupling reactions of 3,6-dihalopyridazines with triaryl- or triheteroarylbismuth compounds were performed under palladium catalysis. The reaction was highly chemoselective, affording functionalized aryl- or heteroarylpyridazinyl chlorides in moderate to good yields. The cross-coupling reactions of 3,6-dihalopyridazines with triaryl- or triheteroarylbismuth compounds were performed under palladium catalysis. The reaction was highly chemoselective, affording functionalized aryl- or heteroarylpyridazinyl chlorides in moderate to good yields. Copyright

6-Phenyl-1,2,4-triazolo[4,3-b]pyridazine hypotensive agents

This disclosure describes novel substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines useful as hypotensive agents.