135034-10-5

Basic information

• Product Name: 3-Chloro-6-iodopyridazine
• Synonyms: 3-Chloro-6-iodopyridazine;Pyridazine, 3-chloro-6-iodo-;3-Chloro-6-iodo-1,2-diazine
• CAS NO: 135034-10-5
• Molecular Formula: C₄H₂ClIN₂
• Molecular Weight: 240.43
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Pyrazines, Pyrimidines & Pyridazines;Heterocyclic Building Blocks
• Mol File: 135034-10-5.mol
• Article Data: 18

Chemical Properties

• Melting Point: 118-120°
• Boiling Point: 327.705 °C at 760 mmHg
• Flash Point: 151.991 °C
• Appearance: /Solid
• Density: 2.188g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.653
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -1.18±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 3-Chloro-6-iodopyridazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-6-iodopyridazine(135034-10-5)
• EPA Substance Registry System: 3-Chloro-6-iodopyridazine(135034-10-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 135034-10-5(Hazardous Substances Data)

Usage

Uses

3-Chloro-6-iodopyridazine is a reactant in the Suzuki-Miyaura coupling reaction as well as a reactant in the synthesis of 6-Chloropyridazine-3-carbonitrile (C368635).

InChI:InChI=1/C4H2ClIN2/c5-3-1-2-4(6)8-7-3/h1-2H

Upstream product

• 1120-95-2 3-chloropyridazine 
• 17973-86-3 3,6-dibromopyridazine 
• 141-30-0 3,6-dichlorpyridazine 

Downstream Products

• 28657-41-2 3-chloro-6-(2'-thienyl)pyridazine 
• 77778-15-5 3-chloro-6-(2-phenylethynyl)pyridazine 
• 258506-68-2 3-chloro-6-(trifluormethyl)pyridazine 
• 1306767-87-2 3-chloro-6-(4-(methoxymethoxy)phenyl)pyridazine 
• 35857-89-7 6-chloropyridazine-3-carbonitrile 
• 949468-94-4 3-chloro-6-(2-methoxyphenyl)pyridazine 
• 20375-65-9 3-chloro-6-phenylpyradazine 
• 2166-07-6 3,6-bis-(4-methoxyphenyl)-pyridazine 
• 58059-31-7 3-chloro-6-(4-methoxyphenyl)pyridazine 
• 1429255-36-6 3-chloro-6-(3-(methoxycarbonyl)phenyl)pyridazine 
• 78784-66-4 3-chloro-6-(pyridin-3-yl)pyridazine 
• 66548-52-5 3-chloro-6-(4-fluorophenyl)pyridazine 
• 66548-88-7 3-chloro-6-(α,α,α-trifluoro-p-tolyl)pyridazine 
• 66548-54-7 3-chloro-6-(4-cyano-phenyl)-pyridazine 

Relevant articles and documents

Desymmetrization of dichloroazaheterocycles

3,6-Dichloropyridizine 1a was converted in good yield into its mono-iodo derivative 1b when treated with a mixture of hydriodic acid and sodium iodide. Pure samples of the mono-iodo derivatives 2b, 3b and 4b could not be obtained from their corresponding dichlorinated precursors with these reagents. Compounds 1b and 4b underwent palladium catalysed Suzuki, Sonogashira and other coupling reactions.

13C nuclear magnetic resonance spectra of 3,6-disubstituted pyridazines

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PESTICIDALLY ACTIVE TETRACYCLIC HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS

Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.

PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS

Polycyclic derivatives of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts salts, stereoisomers, enantiomers, tautomers and N-oxides of those compounds, can be used as insecticides and can be prepared in a manner known per se.