666234-82-8

Basic information

• Product Name: (S)-3-(Dimethylamino)-1,2-propanediol
• Synonyms: (S)-3-(Dimethylamino)-1,2-propanediol
• CAS NO: 666234-82-8
• Molecular Formula: C5H13NO2
• Molecular Weight: 119.16
• Mol File: 666234-82-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 195.9±7.0 °C(Predicted)
• Appearance: /
• Density: 1.047±0.06 g/cm3(Predicted)
• PKA: 14.13±0.20(Predicted)
• CAS DataBase Reference: (S)-3-(Dimethylamino)-1,2-propanediol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(Dimethylamino)-1,2-propanediol(666234-82-8)
• EPA Substance Registry System: (S)-3-(Dimethylamino)-1,2-propanediol(666234-82-8)

Safety Data

• Hazardous Substances Data: 666234-82-8(Hazardous Substances Data)

Usage

General Description

(S)-3-(Dimethylamino)-1,2-propanediol, also known as (S)-(+)-3-Dimethylamino-1,2-propanediol, is a synthetic chemical compound with the molecular formula C5H13NO2. It is commonly used as a chiral auxiliary in asymmetric synthesis and as a resolving agent for racemic mixtures. (S)-3-(Dimethylamino)-1,2-propanediol has been used in various drug synthesis processes, particularly in the development and production of pharmaceuticals. It is also utilized in the manufacturing of other organic compounds. (S)-3-(Dimethylamino)-1,2-propanediol is a colorless liquid with a slightly ammoniacal odor, and it is soluble in water and polar organic solvents. It is important to handle and store this compound in accordance with proper safety protocols and regulations.

Upstream product

• 57090-45-6 (2R)-3-chloro-1,2-propanediol 
• 506-59-2 N,N-dimethylammonium chloride 
• 124-40-3 dimethyl amine 

Relevant articles and documents

AMINO LIPID BASED IMPROVED LIPID FORMULATION

The present invention provides compositions and methods for the delivery of therapeutic agents to cells. In particular, these include novel lipids and nucleic acid-lipid particles that provide efficient encapsulation of nucleic acids and efficient delivery of the encapsulated nucleic aicd to cells in vivo. The compositions of the present invention are highly potent, thereby allowing effective knock-down of specific target protein at relatively low doses. In addition, the compositions and methods of the present invention are less toxic and provide a greater therapeutic index compared to compositions and methods previously known in the art. Formulae (I), (II), (III), (IV).

N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor

This invention relates to compounds of the formula STR1 or an optical isomer thereof wherein R1 and R2 are the same or different and are an alkyl or alkenyl group of 6 to 24 carbon atoms; R3, R4 and R5 are the same or different and are alkyl of 1 to 8 carbon atoms, aryl, aralkyl of 7 to 11 carbon atoms, or when two or three of R3, R4, and R5 are taken together to form quinuclidino, piperidino, pyrrolidino, or morpholino; n is 1 to 8; and X is a pharmaceutically acceptable anion.