66648-21-3

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 58824-56-9 1-(p-bromophenyl)prop-2-en-1-ol 
• 1669-51-8 1‐(4‐bromophenyl)‐3‐phenylpropan‐1‐one 
• 591-50-4 iodobenzene 
• 83-33-0 inden-1-one 
• 589-87-7 1,4-bromoiodobenzene 
• 95-13-6 1-indene 

Downstream Products

• 77605-56-2 [2-(4-Bromo-benzoyl)-phenyl]-acetic acid 
• 79449-12-0 3-(p-cyanophenyl)indene 

Relevant academic research and scientific papers

[Pd]-Catalyzed Intermolecular Coupling and Acid Mediated Intramolecular Cyclodehydration: One-Pot Synthesis of Indenes

An efficient one-pot synthesis of indenes from simple starting materials is presented. This process involves a dual C–C bond formation through an intermolecular Heck coupling reaction followed by acid-mediated intramolecular cyclodehydration. The strategy

Superacid-Mediated Intramolecular Cyclization/Condensation: Facile One-Pot Synthesis of Spirotetracyclic Indanones and Indenes

A facile, superacid-promoted, domino, one-pot synthesis of novel spirotetracyclic indanones through intramolecular Friedel-Crafts acylation/alkylation of α,β-unsaturated cinnamic acid esters is presented. Interestingly, when the β-aryl group contained ele

Joining the rings: The preparation of 2- and 3-indenyl-triptycenes, and curious related processes

The indenyltriptycenes, 1 and 2, where the 3- or 2-indenyl, respectively, is attached at the 9-position of the triptycene, are attractive prototypes of molecular gearing systems that can also incorporate a brake. These molecules have been prepared from their respective indenylanthracenes, 3 and 4, by the [4 + 2] cycloaddition of benzyne to the anthracene fragment, and the rotational barriers about the indenyl-triptycenyl single bonds in 1 (12 kcal mol -1) and 2 (-1) have been measured. The precursor anthracenes, 3 and 4, were prepared by using palladium-catalysed coupling reactions. Unexpectedly, the Heck-type reaction of 9-bromoanthracene, 5, with indene leads to the formation of 3-indenylanthracene 3; moreover, this process is accompanied by a novel palladium-catalysed carbocyclisation reaction leading to the indenophenanthrylene 9. The addition of benzyne to 9-(3-indenyl)anthracene, 3, yields the corresponding indenyltriptycene, 1, and, surprisingly, the anthracenyl methano-bridged phenanthrene 16. It has been demonstrated that 2-arylindenes can act as 1,3-dienes in the [4 + 2] cycloadditions of benzyne. The products 2, 7a, 9 and 16 have been characterised by X-ray crystallography. The Royal Society of Chemistry.

A facile synthesis of 2-arylindenes by Pd-catalyzed direct arylation of indene with aryl iodides

A series of 2-arylindenes were prepared by the reaction of aryl iodides with indene in the presence of a catalytic amount of Pd(OAc)2.

Response of Acidity and Magnetic Rtesonance Properties to Aryl Substitution in Carbon Acids and Derived Carbanions: 2- and 3-Arylindenes

Substitution in the aryl ring of 2- and 3-arylindenes has been used to examine the acidity of these hydrocarbons and the charge density and ion pair structure of their anions.Acidities were measured for the 2-arylindenes both in pure Me2SO and in Me2SO-H2