66648-44-0

Usage

Uses

Used in Pharmaceutical Industry:
N-Feruloyloctopamine is used as a therapeutic agent for its potential health benefits, including its antioxidant and anti-inflammatory properties. It is being studied for its potential role in promoting cardiovascular health and improving blood circulation, as well as its antimicrobial and anti-cancer properties.
Used in Nutritional Supplements:
N-Feruloyloctopamine is used as a nutritional supplement to provide potential health benefits due to its antioxidant and anti-inflammatory properties. It may help support cardiovascular health and improve blood circulation, making it a valuable addition to dietary supplements.
Used in Functional Foods:
N-Feruloyloctopamine is used as an ingredient in functional foods to enhance their health-promoting properties. Its presence in these foods can contribute to the overall antioxidant and anti-inflammatory effects, as well as support cardiovascular health and improve blood circulation.
Used in Cosmetics:
N-Feruloyloctopamine is used in cosmetics for its potential skin health benefits, such as its antioxidant and anti-inflammatory properties. It may help protect the skin from environmental damage and support skin health, making it a valuable ingredient in skincare products.
Used in Agricultural Industry:
N-Feruloyloctopamine is used in the agricultural industry for its potential antimicrobial properties. It may be employed as a natural alternative to synthetic chemicals for crop protection and disease management, promoting sustainable and eco-friendly agricultural practices.

Upstream product

• 104-14-3 octopamine 
• 56254-05-8 ferulic acid N-hydroxysuccinimidyl ester 
• 121-33-5 vanillin 
• 1135-24-6 (E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid 

Downstream Products

• 66648-48-4 triacetyl N-trans-feruloyl octopamine 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships and effects of phenylpropanoid amides of octopamine and dopamine on tyrosinase inhibition and antioxidation

Phenylpropanoid amides of octopamine (OA) 1a-1e and dopamine (DA) 2a-2e were synthesised and the structure-activity relationships (SARs) for antioxidant and tyrosinase inhibition activities were analysed. Among synthesised compounds, 2c, which contains two catechol moieties, exhibited the most DPPH radical-scavenging activity (EC50 = 16.2 ± 2.4 μM), and 1d exhibited significant tyrosinase inhibitory activity (IC50 = 5.3 ± 1.8 μM). Interestingly, with the same acid moiety, OA derivatives showed more inhibitory effect on tyrosinase than did compounds derived from DA, whereas DA derivatives were found to have higher antioxidant activity than compounds derived from OA. The relationship between their structures and their potencies, demonstrated in the current study, will be useful for the design of optimal agents.

Formation of hydroxycinnamoylamides and α-hydroxyacetovanillone in cell cultures of Solanum khasianum

In elicitor-elicited photomixotrophic Solanum khasianum cell cultures, nine phenolic compounds accumulated in the cell culture medium. They were isolated and structurally identified at the cis- and trans-isomers of N-p- coumaroyloctopamine, N-feruloyloctopamine, N-p-coumaroyltyramine and N- feruloyltyramine as well as α-hydroxyacetovanillone. The cis-isomers of the hydroxycinnamoyl moieties were only formed during illumination of the cultures. The hydroxycinnamoylamides showed a transient accumulation with maximum values between 6 and 24 hr after elicitation, depending on the compound. The decrease of the compounds is very likely a peroxidase-mediated reaction.