66648-45-1

Usage

Uses

Used in Pharmaceutical Applications:
N-p-Coumaroyloctopamine is used as a bioactive compound for its potential health benefits. Its presence in certain plants suggests that it may possess therapeutic properties, although further research is needed to fully understand its effects and potential applications in medicine.
Used in Biochemical Research:
N-p-Coumaroyloctopamine is used as a subject of study in the field of biochemistry. Scientists are interested in exploring its chemical properties, interactions with other compounds, and potential applications in drug development and understanding biological processes.
Used in Plant-Based Medicine:
N-p-Coumaroyloctopamine is used as a component in traditional plant-based medicines. Its presence in medicinal plants like Zanthoxylum piperitum and Prunus mume indicates that it may contribute to the therapeutic effects of these plants, and it is being investigated for its potential role in treating various health conditions.
Used in Food Industry:
N-p-Coumaroyloctopamine is used as a natural flavoring agent and preservative in the food industry. Its presence in certain plant-derived products may contribute to the taste, aroma, and shelf life of food items, making it a valuable component in the development of natural food additives.

Upstream product

• 104-14-3 octopamine 
• 88492-43-7 4-hydroxycinnamic acid N-hydroxysuccinimide ester 
• 123-08-0 4-hydroxy-benzaldehyde 
• 7400-08-0 p-Coumaric Acid 

Downstream Products

• 66648-49-5 triacetyl N-trans-p-coumaroyl octopamine 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships and effects of phenylpropanoid amides of octopamine and dopamine on tyrosinase inhibition and antioxidation

Phenylpropanoid amides of octopamine (OA) 1a-1e and dopamine (DA) 2a-2e were synthesised and the structure-activity relationships (SARs) for antioxidant and tyrosinase inhibition activities were analysed. Among synthesised compounds, 2c, which contains two catechol moieties, exhibited the most DPPH radical-scavenging activity (EC50 = 16.2 ± 2.4 μM), and 1d exhibited significant tyrosinase inhibitory activity (IC50 = 5.3 ± 1.8 μM). Interestingly, with the same acid moiety, OA derivatives showed more inhibitory effect on tyrosinase than did compounds derived from DA, whereas DA derivatives were found to have higher antioxidant activity than compounds derived from OA. The relationship between their structures and their potencies, demonstrated in the current study, will be useful for the design of optimal agents.

Formation of hydroxycinnamoylamides and α-hydroxyacetovanillone in cell cultures of Solanum khasianum

In elicitor-elicited photomixotrophic Solanum khasianum cell cultures, nine phenolic compounds accumulated in the cell culture medium. They were isolated and structurally identified at the cis- and trans-isomers of N-p- coumaroyloctopamine, N-feruloyloctopamine, N-p-coumaroyltyramine and N- feruloyltyramine as well as α-hydroxyacetovanillone. The cis-isomers of the hydroxycinnamoyl moieties were only formed during illumination of the cultures. The hydroxycinnamoylamides showed a transient accumulation with maximum values between 6 and 24 hr after elicitation, depending on the compound. The decrease of the compounds is very likely a peroxidase-mediated reaction.