6665-97-0

Basic information

• Product Name: 2,6-Dimethoxynitrobenzene 98%
• Synonyms: 2,6-Dimethoxynitrobenzene 98%;2,6-Dimethoxy-1-nitrobenzene;Nsc291284;2-Nitroresorcinol dimethyl ether;2,6-Dimethoxynitrobenzene98%
• CAS NO: 6665-97-0
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.16
• Product Categories: blocks;NitroCompounds
• Mol File: 6665-97-0.mol
• Article Data: 13

Chemical Properties

• Melting Point: 129-133°C
• Boiling Point: 315℃
• Flash Point: 154℃
• Appearance: /
• Density: 1.226
• Vapor Pressure: 0.000855mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,6-Dimethoxynitrobenzene 98%(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethoxynitrobenzene 98%(6665-97-0)
• EPA Substance Registry System: 2,6-Dimethoxynitrobenzene 98%(6665-97-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 6665-97-0(Hazardous Substances Data)

Usage

General Description

2,6-Dimethoxynitrobenzene 98% is a chemical compound that is derived from nitrobenzene. It is a pale yellow solid with a high purity of 98%. 2,6-Dimethoxynitrobenzene 98% is commonly used in the chemical industry as an intermediate for the synthesis of various organic compounds, including dyes, pharmaceuticals, and agrochemicals. It is also used in the production of rubber chemicals and as a raw material for the manufacture of pesticides. 2,6-Dimethoxynitrobenzene 98% is known for its high reactivity and is handled and stored with caution due to its potential hazards.

InChI:InChI=1/C8H9NO4/c1-12-6-4-3-5-7(13-2)8(6)9(10)11/h3-5H,1-2H3

Upstream product

• 601-89-8 2-nitroresorcinol 
• 77-78-1 dimethyl sulfate 
• 89-41-8 4-methoxy-3-nitrobenzoic acid 
• 121-43-7 Trimethyl borate 
• 16932-44-8 2-iodo-1,3-dimethoxybenzene 
• 108-46-3 recorcinol 
• 151-10-0 1,3-Dimethoxybenzene 
• 74-88-4 methyl iodide 

Downstream Products

• 3114-61-2 2-nitroresorcinol monomethyl ether 
• 601-89-8 2-nitroresorcinol 
• 1150-40-9 1,3-dimethoxy-2,4,6-trinitrobenzene 
• 52898-79-0 3-(2,6-dimethoxyphenyl)-2-methyl-3H-quinazolin-4-one 
• 936744-38-6 3-(2,6-dimethoxyphenyl)-2-[(E)-2-(2-hydroxy-3-methoxyphenyl)vinyl]-3H-quinazolin-4-one 
• 1344112-22-6 (3-amino-2,4-dimethoxyphenyl)(3,4,5-trimethoxyphenyl)methanone 
• 1344112-21-5 N-[2,6-dimethoxy-3-(3,4,5-trimethoxybenzoyl)phenyl]acetamide 
• 905752-06-9 2,4-dimethoxy-3-nitro-1-iodobenzene 
• 7169-01-9 2,4-dimethoxy-3-nitro-benzoic acid 
• 7169-04-2 4,6-Dimethoxy-5-nitro-isophthalsaeuredimethylester 
• 7169-03-1 4,6-Dimethoxy-5-nitro-isophthalsaeure 
• 7169-15-5 5-Nitro-4,6-dimethoxy-isophthalsaeure-dichlorid 
• 7184-33-0 5-Nitro-4,6-dimethoxy-1,3-bis-diazoacetyl-benzol 
• 857835-16-6 1-(2,6-dimethoxy-phenyl)-piperidine 

Relevant articles and documents

Expanding the Balz–Schiemann Reaction: Organotrifluoroborates Serve as Competent Sources of Fluoride Ion for Fluoro-Dediazoniation

The Balz–Schiemann reaction endures as a method for the preparation of (hetero)aryl fluorides yet is eschewed due to the need for harsh conditions or high temperatures along with the need to isolate potentially explosive diazonium salts. In a departure from these conditions, we show that various organotrifluoroborates (RBF3?s) may serve as fluoride ion sources for solution-phase fluoro-dediazoniation in organic solvents under mild conditions. This methodology was successfully extended to a one-pot process obviating aryl diazonium salt isolation. Sterically hindered (hetero)anilines are fluorinated under unprecedentedly mild conditions in good-to-excellent yields. Taken together, this work expands the repertoire of RBF3?s to act as fluorine ion sources in an update to the classic Balz–Schiemann reaction.

Synthesis of aryl ethers from benzoates through carboxylate-directed C-H-activating alkoxylation with concomitant protodecarboxylation

One in, one out: In the presence of a copper/silver bimetallic catalyst system, aromatic carboxylate salts undergo ortho C-H alkoxylation with concomitant loss of the carboxylate directing group in a protodecarboxylation step (see scheme, FG=functional group). This process provides a convenient synthetic access to the important class of aromatic ethers from widely available carboxylic acids. Copyright

Aromatic nitration with bismuth nitrate in ionic liquids and in molecular solvents: A comparative study of Bi(NO3)3·5H 2O/[bmim][PF6] and Bi(NO3)3· 5H2O/1,2-DCE systems

A suspension of bismuth nitrate pentahydrate (BN) in [bmim][PF6] or [bmim][BF4] imidazolium ionic liquid (IL) is an effective reagent for ring nitration of activated aromatics under mild conditions without the need for external promoters. Nitration can also be effected in 1,2-DCE, MeCN, or MeNO2 without additives. Nitration of activated arenes (anisole, toluene, ethylbenzene, cumene, p-xylene, mesitylene, durene, and 1,3-dimethoxybenzene) is considerably faster (time to completion) in BN/[bmim][PF6] relative to BN/1,2-DCE and there are also differences in isomer distributions (for anisole, toluene, and ethylbenzene). With introduction of strongly deactivating substituents (-CHO; -MeCO; -NO 2) the BN/IL system is no longer active but reactions still proceed with BN/1,2-DCE in reasonable yields. The ready availability and low cost of BN, simple operation, and absence of promoters, coupled to recycling and reuse of the IL, provide an attractive alternative to classical nitration methods for activated arenes. Switching from Bi(NO3)3·5H 2O/[bmim][PF6] to Bi(NO3)3· 5H2O/1,2-DCE increases the scope of the substrates that can be nitrated.