66661-71-0

Basic information

• Product Name: 2(5H)-Furanone, 5-hydroxy-3-phenyl-
• CAS NO: 66661-71-0
• Molecular Formula: C10H8O3
• Molecular Weight: 176.172
• Mol File: 66661-71-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 5-hydroxy-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 5-hydroxy-3-phenyl-(66661-71-0)
• EPA Substance Registry System: 2(5H)-Furanone, 5-hydroxy-3-phenyl-(66661-71-0)

Safety Data

• Hazardous Substances Data: 66661-71-0(Hazardous Substances Data)

Upstream product

• 66661-75-4 C₁₂H₁₄N₂O₂ 
• 101-97-3 Ethyl 2-phenylethanoate 
• 66661-68-5 4-(Dimethylhydrazono)-2-phenylcrotonsaeure-ethylester 
• 71237-44-0 methyl 3-phenyl-2-furoate 
• 98-80-6 phenylboronic acid 
• 169772-63-8 3-phenyl-2-furoic acid 

Downstream Products

• 57200-23-4 3-phenyl-2(5H)-furanone 
• 78646-98-7 4-(2-oxo-3,3a,8,8a-tetrahydro-2H-indeno<2,1-b>furan-3-ylidenemethoxy)-2-phenylbut-2-en-4-olide 
• 78646-91-0 4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopentafuran-3-ylidenemethoxy)-2-phenylbut-2-en-4-olide 
• 112895-80-4 Sodium; 4-hydroxy-2-phenyl-butyrate 
• 6836-98-2 3-phenyldihydrofuran-2-one 

Relevant articles and documents

Regioselective entry to bromo-γ-hydroxybutenolides: Useful building blocks for assemblying natural product-like libraries

(Chemical Equation Presented) We report a regioselective entry to 3-bromo- and 4-bromo-5-hydroxy-5H-furan-2-ones by photooxidation of 3-bromofuran with a singlet oxygen in the presence of a suitable base. By this procedure, a variety of 3-substituted γ-hydroxybutenolides have become for the first time easily accessible. Strategies employing these highly functionalized building blocks for the preparation of focused libraries of natural-like molecules are also discussed.