6667-08-9Relevant academic research and scientific papers
Metal-Free Thiolation of Imidazopyridines with Functionalized Haloalkanes Using Elemental Sulfur
Zhang, Jun-Rong,Zhan, Ling-Zhi,Wei, Liang,Ning, Yun-Yun,Zhong, Xiao-Lin,Lai, Jing-Xiong,Xu, Li,Tang, Ri-Yuan
, p. 533 - 543 (2018/01/27)
The assembly of two functional molecules via a sulfur linking atom allows an access to a diverse array of thioether-containing compounds. Herein, we disclose a metal-free thiolation of imidazopyridines with a variety of functionalized haloalkanes using elemental sulfur. (Figure presented.).
Sulfuration derivative of imidazopyridine and preparation method thereof
-
Paragraph 0070-0075, (2018/03/23)
The invention discloses a sulfuration derivative of imidazopyridine and a preparation method thereof. The sulfuration derivative of imidazopyridine has a structure as shown in a general formula whichis described in the specification. The preparation method for the sulfuration derivative of imidazopyridine has the advantages of simple process flow, low cost, friendliness to environment, etc. According to the invention, cheap sulfur powder and alkylogen which is easily available on the market and has abundant function groups are used for replacing thiophenol and mercaptan reagents; only alkaliis added in the process of reaction for catalysis; the preparation method is friendly to environment, simple to operate, and mild in conditions; the function groups of substrates are good in compatibility; moreover, the sulfuration derivative prepared in the invention has diversified function groups, an imidazopyridine advantaged skeleton and thioether active fragments, and has potential application value in the fields of development of new drugs and medical research.
Visible-light-induced regioselective sulfenylation of imidazopyridines with thiols under transition metal-free conditions
Rahaman, Rajjakfur,Das, Shivasish,Barman, Pranjit
supporting information, p. 141 - 147 (2018/01/12)
A metal-free visible-light-promoted regioselective C-3 sulfenylation of imidazo[1,2-a]pyridines and indoles using thiols has been developed via C(sp2)-H functionalization. This method provides direct access to a wide range of structurally diver
One-Pot Three-Component Synthesis of Alkylthio-/Arylthio- Substituted Imidazo[1,2-a]pyridine Derivatives via C(sp2)–H Functionalization
Zhu, Wenhui,Ding, Yingcai,Bian, Zhaogang,Xie, Ping,Xu, Baojun,Tang, Qiujie,Wu, Wei,Zhou, Aihua
, p. 2215 - 2221 (2017/07/07)
Sulfenylation is an important transformation to generate C?S bonds in organic synthesis. Here, two three-component synthetic protocols have been developed by using imidazo[1,2-a]pyridine, inorganic, odorless S8 and alcohols or arylboronic acids
Direct thiolation of methoxybenzenes with thiols under metal-free conditions by iodine catalysis
Yan, Kelu,Yang, Daoshan,Sun, Pengfei,Wei, Wei,Liu, Yao,Li, Guoqing,Lu, Shenglei,Wang, Hua
supporting information, p. 4792 - 4795 (2015/07/20)
A direct thiolation of methoxybenzenes with various thiols has been developed. The protocol uses inexpensive reagents: catalytic iodine in the presence of DTBP. Importantly, no base or ligand was necessary. This method opens a new avenue to a variety of valuable thioethers that would be more difficult to access with traditional methods.
Iodine-triphenylphosphine mediated sulfenylation of imidazoheterocycles with sodium sulfinates
Huang, Xuhu,Wang, Shucheng,Li, Bowen,Wang, Xin,Ge, Zemei,Li, Runtao
, p. 22654 - 22657 (2015/03/14)
An efficient approach to sulfenyl imidazoheterocycles has been developed via iodine-triphenylphosphine mediated direct sulfenylation of imidazoheterocycles with sodium sulfinates. The reactions proceed smoothly under transition-metal-free conditions with a broad range of substrate scope, giving the desired products in moderate to excellent yields. This journal is
