66679-67-2

Upstream product

• 898050-75-4 3-(3-methoxyphenyl)-2-methylsulfanyl-3H-quinazolin-4-one 
• 56671-19-3 3-(3-methoxyphenyl)-2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 536-90-3 m-Anisidine 
• 34881-38-4 (3-Methoxy-phenyl)-dithiocarbamic acid methyl ester 

Downstream Products

• 85773-32-6 3-[4-(3-Methoxy-phenyl)-5-oxo-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinazolin-1-yl]-propionic acid ethyl ester 
• 67811-59-0 4-(3-methoxyphenyl)-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one 
• 68357-52-8 4-(3-methoxyphenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one 
• 1105576-14-4 1-ethyl-4-(3-methoxyphenyl)-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one 
• 1105576-16-6 1-chloromethyl-4-(3-methoxyphenyl)-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one 
• 1105576-15-5 4-(3-methoxyphenyl)-1-propyl-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one 
• 1256932-63-4 2-(N'-(phenyl-benzylidene)-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 1256932-52-1 C₂₃H₁₇N₅O₃ 
• 1256932-50-9 2-(N'-cyclohexylidene-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 1256932-62-3 2-(N'-(4-methyl-benzylidene)-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 66679-93-4 2-(N'-(4-chloro-benzylidene)-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 1256932-55-4 2-(N'-(2-chloro-benzylidene)-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 1256932-59-8 2-(N'-(4-nitro-benzylidene)-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 
• 1256932-53-2 2-(N'-benzylidene-hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one 

Relevant academic research and scientific papers

Synthesis and analgesic, anti-inflammatory activities of 3-(3-methoxyphenyl)-2-substituted amino-quinazolin-4 (3H)-ones

A variety of novel 3-(3-methoxyphenyl)-2- substituted amino-quinazolin- 4(3H)-ones were synthesized by reacting the amino group of 2-hydrazino-3-(3- methoxyphenyl)- quinazolin-4(3H)-one with a variety of aldehydes and ketones. The starting material 2-hydrazino-3-(3- methoxyphenyl)-quinazolin-4(3H)-one was synthesized from 3-methoxy aniline. The title compounds were investigated for analgesic, anti-inflammatory, and ulcerogenic behavior. Among these the compound 2-(1-methyl butylidene- hydrazino)-3-(3-methoxyphenyl)-3H-quinazolin-4-one (AS3) emerged as the most active compound for the analgesic activity, while the compound 2-(1-ethyl propylidene- hydrazino)-3-(3-methyoxyphenyl)-3H-quinazolin- 4- one (AS2) showed most potent anti-inflammatory activity of the series and these compounds are moderately more potent when compared to the reference standard diclofenac sodium. Interestingly the test compounds showed only mild ulcerogenic potential when compared to acetylsalicylic acid. Springer Science+Business Media, LLC 2010.

4-(3-Methoxyphenyl)-1-substituted-4H-[1,2,4]triazolo[4,3-a] quinazolin-5-ones: New class of H1-antihistaminic agents

A series of 1-substituted-4-(3-methoxyphenyl)-4H-[1,2,4]triazolo[4,3-a] quinazolin-5-ones were synthesized by the cyclization of 2-hydrazino-3-(3- methoxyphenyl)-3H-quinazolin-4-one with various electrophile. The starting material 2-hydrazino-3-(3-methoxy

Heterocycles as cholecystokinin (CCK) ligands

Novel quinazolinone derivatives with good binding affinity for the CCK-A and CCK-B receptors, pharmaceutical compositions containing them and methods of using them are taught. The compounds are useful agents to suppress appetite, reduce gastric acid secre