666824-74-4

Upstream product

• 6279-86-3 methanetricarboxylic acid triethyl ester 
• 612058-33-0 (1R)-(1-phenylethoxy)(diphenyl)phosphine 
• 1445-91-6 (S)-1-phenylethanol 

Downstream Products

• 4593-90-2 (S)-2-phenylbutanoic acid 
• 1134-71-0 ethyl (3R)-3-phenylbutanoate 
• 772-14-5 (R)-3-phenylbutyric acid 
• 128677-90-7 (4R)-3-(3'R)-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 

Relevant academic research and scientific papers

OPIOID RECEPTOR MODULATORS AND PRODUCTS AND METHODS RELATED THERETO

Compounds are provided having the structure of Formula (I): or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope, or salt thereof, wherein A, B, L, R3, R4, R5, R6, R8, m and n are as defined herein. Such compounds modulate the opioid receptor, particulare the mu-opioid receptor (MOR) and/or the kappa-opioid receptor (KOR), and/or the delta-opioid receptor (DOR). Products containing such compounds, as well as methods for their use and preparation, are also provided.

Stereoselective carbon-carbon bond forming reactions between various chiral alkyl aryl carbinols and triethyl methanetricarboxylate by oxidation-reduction condensation using alkyl diphenylphosphinites

Oxidation-reduction condensation reactions between alkyl diphenylphosphinites derived from chiral alkyl aryl carbinols and triethyl methanetricarboxylate proceeded smoothly to afford the corresponding condensation products in good yields with inversion of stereochemistries. Copyright