128677-90-7

Upstream product

• 772-14-5 (R)-3-phenylbutyric acid 
• 40217-17-2 (R)-4-(phenylmethyl)-2-oxazolidinone 
• 372504-89-7 (R)-4-benzyl-2-oxazolidinone lithium salt 
• 128677-86-1 C₁₅H₂₀O₃ 
• 3282-30-2 pivaloyl chloride 
• 1517-69-7 (R)-1-phenylethanol 
• 666824-74-4 triethyl (2S)-2-phenylpropane-1,1,1-tricarboxylate 
• 4593-90-2 (S)-2-phenylbutanoic acid 

Downstream Products

• 128707-87-9 (4S)-3-(2'R,3'S)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 128707-89-1 (4R)-3-(2'S,3'S)-2'-azido-3'-(phenylbutanoyl)-4-(phenylmethyl)-2-oxazolidinone 
• 143251-56-3 (R)-4-Benzyl-3-((2S,3S)-2-bromo-3-phenyl-butyryl)-oxazolidin-2-one 
• 128677-93-0 (2R)-azido-(3S)-phenylbutanoic acid 
• 59905-30-5 threo-D-(2R,3S)-β-methylphenylalanine 
• 128677-95-2 (2S,3S)-2-azido-3-phenylbutanoic acid 
• 25488-25-9 (2S,3S)-methylphenylalanine 

Relevant academic research and scientific papers

BETA-TETRAZOLYL-PROPIONIC ACIDS AS METALLO-BETA-LACTAMASE INHIBITORS

The present invention relates to compounds of formula I that are metallo-β-lactamase inhibitors, the synthesis of such compounds, and the use of such compounds for use with β-lactam antibiotics for overcoming resistance.

Asymmetric synthesis of unusual amino acids: An efficient synthesis of optically pure isomers of β-methylphenylalanine

Substitution of the diastereotopic β-hydrogens of many α-amino acids provides an approach to the three dimensional topographic control of peptide structure. Asymmetric synthesis of the desired amino acids is needed to facilitate these studies. All four in

ASYMMETRIC SYNTHESIS OF UNUSUAL AMINO ACIDS: SYNTHESIS OF OPTICALLY PURE ISOMERS OF β-METHYLPHENYLALANINE

All the four individual isomers of β-methylphenylalanine have been synthesized in very high optical purities by utilizing in part the chiral imide enolate bromination methodology of Evans and co-workers.