66684-77-3

Upstream product

• 49678-08-2 3-(4-nitrophenyl)-propenal 
• 108-59-8 malonic acid dimethyl ester 
• 1734-79-8 3-(4-nitrophenyl)-2-propenal 

Relevant academic research and scientific papers

Asymmetric michael addition of ketones to alkylidene malonates and allylidene malonates via enamine - Metal lewis acid bifunctional catalysis

Novel enamine-metal Lewis acid bifunctional catalysts were successfully applied to the asymmetric Michael addition of ketones to alkylidene malonates, offering excellent stereoselectivity (up to >99% ee and >99:1 dr). The asymmetric Michael addition of ketones to allylidene malonates was also achieved.