666845-36-9Relevant academic research and scientific papers
Fe(Cp)2BF4: An efficient lewis acid catalyst for the aminolysis of epoxides
Yadav, Geeta Devi,Chauhan, Manmohan Singh,Singh, Surendra
, p. 629 - 634 (2014/03/21)
Ferrocenium tetrafluoroborate [Fe(Cp)2BF4] is an efficient Lewis acid catalyst for the aminolysis of aromatic, aliphatic, and cyclic epoxides using aniline and substituted anilines as the nucleophile to provide regioselective β-amino alcohols in 61-97% yields under solvent-free conditions at room temperature. The ring opening of cyclohexene oxide with aliphatic amines gave 2-aminocyclohexanols in 33-98% yields at 60 °C under solvent-free conditions. Georg Thieme Verlag Stuttgart New York.
N-Fluorobenzenaminium tetrafluoroborate generated in situ by aniline and Selectfluor as a reusable catalyst for the ring opening of epoxides with amines under microwave irradiation
Chauhan, Manmohan Singh,Yadav, Geeta Devi,Hussain, Firasat,Singh, Surendra
, p. 3945 - 3952 (2015/02/19)
The ring opening of epoxides with aromatic and aliphatic amines was carried out under solvent free conditions using N-fluorobenzenaminium tetrafluoroborate (2 mol%) generated in situ by the reaction of aniline and Selectfluor as a catalyst with microwave irradiation. Excellent yields of β-amino alcohols were obtained. The catalyst also results in the retention of the stereochemistry for the ring opening of enantiopure epoxide with amine. The catalyst was recovered and reused up to 4 cycles for the ring opening of cyclohexene oxide with aniline. This journal is
Highly enantioselective organocatalytic syn- And anti-aldol reactions in aqueous medium
Raj, Monika,Parashari, Gopal S.,Singh, Vinod K.
supporting information; scheme or table, p. 1284 - 1288 (2009/12/25)
We have synthesized chiral diamines that efficiently catalyze the syn- and anti-aldol reactions in aqueous medium with high diastereo- and enantioselectivities. The product, thus obtained, was further reduced selectively to give syn-configured 1,2,3-triol
Use of diamines containing the α-phenylethyl group as chiral ligands in the asymmetric hydrosilylation of prochiral ketones
Mastranzo, Virginia M.,Quintero, Leticia,De Parrodi, Cecilia Anaya,Juaristi, Eusebio,Walsh, Patrick J.
, p. 1781 - 1789 (2007/10/03)
Chiral diamines 1-7 were used in the enantioselective hydrosilylation of prochiral aromatic and aliphatic ketones. Some of these ligands combine chiral backbones and chiral N,N′-α-phenylethyl substituents that give rise to synergistic effects between these two groups and lead to catalysts that exhibit high enantioselectivity.
Preparation of trans-1,2-diaminocyclohexane derivatives by lithium perchlorate catalyzed ring opening of aziridines
De Parrodi,Vazquez,Quintero,Juaristi
, p. 3295 - 3302 (2007/10/03)
N,N′-Dialkylated trans-1,2-diaminocyclohexane derivatives were synthesized with good overall yield via reaction of the corresponding N-alkylated cyclohexene aziridine with amines, in the presence of lithium perchlorate as catalyst.
Preparation of enantiomerically pure cis- and trans-N(propionyl)hexahydrobenzoxazolidin-2-ones
De Parrodi, Cecilia Anaya,Juaristi, Eusebio,Quintero, Leticia,Clara-Sosa, Angel
, p. 1075 - 1082 (2007/10/03)
A high-yield, five-step synthesis of novel enantiomerically pure cis- and trans-N-(propionyl)-hexahydrobenzoxazolidin-2-5a-d from cyclohexene oxide and (S)-α-methylbenzylamine is described. The highly diastereoselective benzylation of 5b is also described
