66695-40-7Relevant academic research and scientific papers
Unexpected domino reaction via Pd-catalyzed Sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and cyclization to synthesize quinoline derivatives
Gao, Guo-Lin,Niu, Yan-Ning,Yan, Ze-Yi,Wang, Hong-Li,Wang, Gang-Wei,Shaukat, Ali,Liang, Yong-Min
supporting information; experimental part, p. 1305 - 1308 (2010/04/26)
(Chemical Equation Presented) A domino reaction via palladium-catalyzed Sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and then cyclization to form quinoline derivatives has been developed. The reaction conditions and the scope of the process are examined, and a plausible mechanism is proposed. The procedure is simple, rapid, and general, and the substrates are readily available. 2010 American Chemical Society.
