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1,3-dimethyl-4-phenyl-1,2,3,6-tetrahydropyridine, also known as 1,3-dimethyl-4-phenyl-THP, is a chemical compound belonging to the class of tetrahydropyridines. It is a colorless liquid with a molecular formula of C14H19N and a molecular weight of 201.31 g/mol. 1,3-dimethyl-4-phenyl-1,2,3,6-tetrahydropyridine is characterized by the presence of a six-membered nitrogen-containing ring, with two methyl groups at the 1st and 3rd positions, and a phenyl group at the 4th position. 1,3-dimethyl-4-phenyl-THP is synthesized through various chemical reactions and is used as an intermediate in the production of pharmaceuticals and other organic compounds. Due to its potential neurotoxic effects, it is essential to handle 1,3-dimethyl-4-phenyl-1,2,3,6-tetrahydropyridine with caution and proper safety measures.

6672-51-1

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6672-51-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6672-51-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,7 and 2 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6672-51:
(6*6)+(5*6)+(4*7)+(3*2)+(2*5)+(1*1)=111
111 % 10 = 1
So 6672-51-1 is a valid CAS Registry Number.

6672-51-1Relevant academic research and scientific papers

Synthesis and toxicity toward nigrostriatal dopamine neurons of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) analogues

Fries,De Vries,Hazelhoff,Horn

, p. 424 - 427 (1986)

Six compounds having structural features in common with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were synthesized and tested in mice for the ability to produce a prolonged decrease in nigrostriatal dopamine (DA) and DA metabolites. The compounds that were prepared and tested include the ester elimination products of the analgetic drugs α-prodine and trimeperidine. None of the compounds in this study, except for MPTP, produced significant neurotoxic effects in the mouse model. The study shows that minor changes in the tetrahydropyridine ring of MPTP result in a marked decrease in neurotoxicity.

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